Circular RNAs as promising biomarkers in cancer: detection, function, and beyond

S Li, L Han - Genome medicine, 2019 - Springer
Editorial summary Circular RNAs (circRNAs) are 3′–5′ covalently closed RNA rings
produced from back-splicing of precursor mRNA in eukaryotes. Recent studies, using both …

Circular RNAs in cancer–lessons learned from microRNAs

M Dragomir, GA Calin - Frontiers in oncology, 2018 - frontiersin.org
Circular RNAs (circRNA) are RNA molecules built from fragments of linear pre-messenger
RNAs and other linear RNA species through a process termed “back-splicing” in which the …

Circular RNAs: biogenesis, function, and a role as possible cancer biomarkers

L Bolha, M Ravnik-Glavač… - International journal of …, 2017 - Wiley Online Library
Circular RNAs (circRNAs) are a class of noncoding RNAs (ncRNAs) that form covalently
closed continuous loop structures, lacking the terminal 5′ and 3′ ends. CircRNAs are …

Characterization of circular RNAs with advanced sequencing technologies in human complex diseases

H Ruan, PC Wang, L Han - Wiley Interdisciplinary Reviews …, 2023 - Wiley Online Library
Circular RNAs (circRNAs) are one category of non‐coding RNAs that do not possess 5′
caps and 3′ free ends. Instead, they are derived in closed circle forms from pre‐mRNAs by …

[HTML][HTML] Circular RNAs in cancer

DH Bach, SK Lee, AK Sood - Molecular Therapy-Nucleic Acids, 2019 - cell.com
Circular RNAs (circRNAs) are a class of single-stranded closed RNA molecules that are
formed by precursor mRNA back-splicing or skipping events of thousands of genes in …

Circular RNAs as biomarkers for cancer

L Xia, M Song, M Sun, F Wang, C Yang - Circular RNAs: biogenesis and …, 2018 - Springer
As a type of novel noncoding RNAs, circular RNAs (circRNAs) have attracted great interest
due to its different characteristics from linear RNAs. They are abundantly and stably present …

Recent progress in circular RNAs in human cancers

G Huang, S Li, N Yang, Y Zou, D Zheng, T Xiao - Cancer letters, 2017 - Elsevier
Circular RNAs (circRNAs) are a large class of endogenous RNAs, formed by exon skipping
or back-splicing events as covalently closed loops, which are expressed abundantly in …

[HTML][HTML] Circular RNAs: crucial regulators in the human body

Y Wang, T Lu, Q Wang, J Liu… - Oncology reports, 2018 - spandidos-publications.com
Circular RNAs (circRNAs) belong to a new type of endogenous non‑coding RNAs (ncRNAs)
that are derived from exons and/or introns, and are widely distributed in mammals. The …

The emerging functions and roles of circular RNAs in cancer

S Qu, Z Liu, X Yang, J Zhou, H Yu, R Zhang, H Li - Cancer letters, 2018 - Elsevier
Circular RNAs (circRNAs) are a class of single-stranded closed RNA molecules that
undergo a specific backsplicing from pre-mRNA. With the application of high-throughput …

New molecular mechanisms and clinical impact of circRNAs in human cancer

G Fontemaggi, C Turco, G Esposito, S Di Agostino - Cancers, 2021 - mdpi.com
Simple Summary Circular RNAs (circRNAs) belong to a new class of non-coding RNAs
implicated in cellular physiological functions but also in the evolution of various human …