Introduction The finding of antinuclear antibody (ANA) positivity in a healthy individual is
usually of unknown significance and in most cases is benign. However, a subset of such …

Antinuclear antibodies (ANAs) are venerable biomarkers for assessing the diagnosis and
prognosis of patients with autoimmunity. While closely associated with diseases such as …

Objective Antinuclear antibodies (ANAs) are detected in∼ 18% of females, yet autoimmune
disease develops in only 5–8%. Immunologic differences between ANA‐positive healthy …

Introduction The aim of this study was to examine seroconversion and the relationship with
age and inflammation of autoantibodies in a large group of patients attending an outpatient …

Objective. Growing evidence suggests increasing frequencies of autoimmunity and certain
autoimmune diseases, but findings are limited by the lack of systematic data and evolving …

Objective Growing evidence suggests increasing frequencies of autoimmunity and
autoimmune diseases, but findings are limited by the lack of systematic data and evolving …

Background Elevated levels of type I interferons (IFNs) are a characteristic feature of the
systemic autoimmune rheumatic diseases (SARDs) and are thought to play an important …

Background We determined the prevalence of anti-nuclear autoantibodies (ANAs) in the
German adult population and examined the association between ANAs and cardiovascular …

Antinuclear antibodies (ANAs) are a diverse group of autoantibodies that recognize nuclear
macromolecules and their complexes. ANAs represent key biomarkers in the evaluation of …

Objective The spectrum of antinuclear antibodies (ANA s) is changing to include both
nuclear staining as well as cytoplasmic and mitotic cell patterns (CMP s) and accordingly a …