[HTML][HTML] eSNaPD: a versatile, web-based bioinformatics platform for surveying and mining natural product biosynthetic diversity from metagenomes
BVB Reddy, A Milshteyn, Z Charlop-Powers… - Chemistry & biology, 2014 - cell.com
Summary Environmental Surveyor of Natural Product Diversity (eSNaPD) is a web-based
bioinformatics and data aggregation platform that aids in the discovery of gene clusters …
bioinformatics and data aggregation platform that aids in the discovery of gene clusters …
Culture-independent discovery of natural products from soil metagenomes
M Katz, BM Hover, SF Brady - Journal of Industrial Microbiology …, 2016 - academic.oup.com
Bacterial natural products have proven to be invaluable starting points in the development of
many currently used therapeutic agents. Unfortunately, traditional culture-based methods for …
many currently used therapeutic agents. Unfortunately, traditional culture-based methods for …
The confluence of big data and evolutionary genome mining for the discovery of natural products
This review covers literature between 2003–2021 The development and application of
genome mining tools has given rise to ever-growing genetic and chemical databases and …
genome mining tools has given rise to ever-growing genetic and chemical databases and …
A computational framework to explore large-scale biosynthetic diversity
JC Navarro-Muñoz, N Selem-Mojica… - Nature chemical …, 2020 - nature.com
Genome mining has become a key technology to exploit natural product diversity. Although
initially performed on a single-genome basis, the process is now being scaled up to mine …
initially performed on a single-genome basis, the process is now being scaled up to mine …
Metabolomics and genomics in natural products research: complementary tools for targeting new chemical entities
Covering: 2010 to 2021 Organisms in nature have evolved into proficient synthetic chemists,
utilizing specialized enzymatic machinery to biosynthesize an inspiring diversity of …
utilizing specialized enzymatic machinery to biosynthesize an inspiring diversity of …
Integrated metabolomic–genomic workflows accelerate microbial natural product discovery
The pairing of analytical chemistry with genomic techniques represents a new wave in
natural product chemistry. With an increase in the availability of sequencing and assembly of …
natural product chemistry. With an increase in the availability of sequencing and assembly of …
[HTML][HTML] The natural product domain seeker NaPDoS: a phylogeny based bioinformatic tool to classify secondary metabolite gene diversity
New bioinformatic tools are needed to analyze the growing volume of DNA sequence data.
This is especially true in the case of secondary metabolite biosynthesis, where the highly …
This is especially true in the case of secondary metabolite biosynthesis, where the highly …
Microbial natural product databases: moving forward in the multi-omics era
Covering: 2010–2020 The digital revolution is driving significant changes in how people
store, distribute, and use information. With the advent of new technologies around linked …
store, distribute, and use information. With the advent of new technologies around linked …
The natural products atlas: an open access knowledge base for microbial natural products discovery
JA Van Santen, G Jacob, AL Singh, V Aniebok… - ACS central …, 2019 - ACS Publications
Despite rapid evolution in the area of microbial natural products chemistry, there is currently
no open access database containing all microbially produced natural product structures …
no open access database containing all microbially produced natural product structures …
Mining for microbial gems: integrating proteomics in the postgenomic natural product discovery pipeline
C Du, GP van Wezel - Proteomics, 2018 - Wiley Online Library
Natural products (NPs) are a major source of compounds for medical, agricultural, and
biotechnological industries. Many of these compounds are of microbial origin, and, in …
biotechnological industries. Many of these compounds are of microbial origin, and, in …