Sulfur mustard skin lesions: A systematic review on pathomechanisms, treatment options and future research directions

D Rose, A Schmidt, M Brandenburger, T Sturmheit… - Toxicology Letters, 2018 - Elsevier
Sulfur mustard (SM) is a chemical warfare, which has been used for one hundred years.
However, its exact pathomechanisms are still incompletely understood and there is no …

Mechanisms mediating the vesicant actions of sulfur mustard after cutaneous exposure

MP Shakarjian, DE Heck, JP Gray, PJ Sinko… - Toxicological …, 2010 - academic.oup.com
Sulfur mustard (SM), a chemical weapon first employed during World War I, targets the skin,
eyes, and lung. It remains a significant military and civilian threat. The characteristic …

Acute and chronic effects of sulfur mustard on the skin: a comprehensive review

M Ghanei, Z Poursaleh, AA Harandi… - … and ocular toxicology, 2010 - Taylor & Francis
Sulfur mustard (2, 2-dichlorodiethyl sulfide, SM) is one of the vesicant classes of chemical
warfare agents that causes blistering in the skin and mucous membranes, where it can have …

Pathogenesis and treatment of skin lesions caused by sulfur mustard

Z Poursaleh, M Ghanei, F Babamahmoodi… - … and ocular toxicology, 2012 - Taylor & Francis
Objective: Sulfur mustard (SM) exposure intensely causes lesions that range in severity from
mild erythema to blister formation and necrosis. This review will discuss acute and long-term …

Management of sulfur mustard-induced chronic pruritus: a review of clinical trials

Y Panahi, A Sarayani, F Beiraghdar… - … and ocular toxicology, 2012 - Taylor & Francis
Skin is among the most heavily damaged organs upon sulfur mustard (SM) exposure.
Chronic complications due to SM-induced dermatotoxicity are quite frequent among …

Accidental sulfur mustard exposure: a case report

A Schmidt, D Steinritz, KD Rudolf, H Thiermann… - Toxicology letters, 2018 - Elsevier
The clinical progression following a sulfur mustard-induced skin exposure is well
documented in the literature. Upon skin contact and a characteristic latency period, sulfur …

Therapeutic options to treat sulfur mustard poisoning—The road ahead

WJ Smith - Toxicology, 2009 - Elsevier
For the past 15 years the international research community has conducted a basic and
applied research program aimed at identifying a medical countermeasure against chemical …

Advanced biotherapy for the treatment of sulfur mustard poisoning

M Sun, Y Yang, W Meng, Q Xu, F Lin, Y Chen… - Chemico-biological …, 2018 - Elsevier
Context Sulfur mustard (SM), a bifunctional alkylating agent, can react with a variety of
biochemical molecules (DNA, RNA, proteins and other cell components) to cause a series of …

Sulfur mustard: its continuing threat as a chemical warfare agent, the cutaneous lesions induced, progress in understanding its mechanism of action, its long-term …

KJ Smith, CG Hurst, RB Moeller, HG Skelton… - Journal of the American …, 1995 - Elsevier
Although sulfur mustard (SM) has been used as a chemical warfare agent since the early
twentieth century, it has reemerged in the past decade as a major threat around the world …

Molecular toxicology of sulfur mustard-induced cutaneous inflammation and blistering

K Kehe, F Balszuweit, D Steinritz, H Thiermann - Toxicology, 2009 - Elsevier
Sulfur mustard (SM) is a strong alkylating agent, which produces subepidermal blisters,
erythema and inflammation after skin contact. Despite the well-described SM-induced gross …