One of the most significant health problems in the American continent in terms of human
health, and socioeconomic impact is Chagas disease, caused by the protozoan parasite …

Chagas disease is a neglected tropical disease caused by the protozoan Trypanosoma
cruzi. Currently, only nitroheterocyclic nifurtimox (NFX) and benznidazole (BNZ) are …

The trypanocidal action of green tea catechins against two different developmental stages of
Trypanosoma cruzi is reported for the first time. This activity was assayed with the …

Background The current treatment of Chagas disease, endemic in Latin America and
emerging in several countries, is limited by the frequent side effects and variable efficacy of …

The accidental transmission of Chagas' disease by donor blood is recognized as a serious
problem in the Latin America. This paper describes the screening of natural products as …

In the 100 years since the discovery of Chagas disease, only two drugs have been
developed and introduced into clinical practice, and these drugs were introduced over 40 …

This opinion piece presents an approach to standardisation of an important aspect of
Chagas disease drug discovery and development: selecting Trypanosoma cruzi strains for …

Chagas disease, also known as American trypanosomiasis, is caused by the protozoan
parasite Trypanosoma cruzi, which was discovered by the Brazilian Carlos Chagas in 1909 …

Chagas disease, also known as American trypanosomiasis, is caused by infection with the
protozoan parasite Trypanosoma cruzi. The Pan American Health Organization (PAHO) …

Chagas disease (CD), caused by the intracellular protozoan Trypanosoma cruzi, is a
parasitic illness endemic in Latin America. In the centennial after CD discovery by Carlos …