Beta3-adrenoreceptors in cardiovasular diseases: new roles for an “old” receptor
JL Balligand - Current drug delivery, 2013 - ingentaconnect.com
Beta3-adrenoreceptors (B3AR) are traditionally known as metabolic receptors in adipose
tissue, but came into focus in the cardiovascular field after our demonstration of their …
tissue, but came into focus in the cardiovascular field after our demonstration of their …
[HTML][HTML] The beta3 adrenergic receptor in healthy and pathological cardiovascular tissues
LYM Michel, C Farah, JL Balligand - Cells, 2020 - mdpi.com
The third isotype of beta-adrenoreceptors (β3-AR) has recently come (back) into focus after
the observation of its expression in white and beige human adipocytes and its implication in …
the observation of its expression in white and beige human adipocytes and its implication in …
New and emerging therapies and targets: beta-3 agonists
LYM Michel, JL Balligand - Heart Failure, 2017 - Springer
While crucial for the acute physiologic response to stress, the adrenergic system may
become maladaptive upon prolonged stimulation in the course of development of heart …
become maladaptive upon prolonged stimulation in the course of development of heart …
Beta3-adrenergic receptors in cardiac and vascular tissues: emerging concepts and therapeutic perspectives
C Dessy, JL Balligand - Advances in pharmacology, 2010 - Elsevier
Catecholamines released by the orthosympathetic system play a major role in the short-and
long-term regulation of cardiovascular function. Beta1-and beta2-adrenoreceptors (ARs) …
long-term regulation of cardiovascular function. Beta1-and beta2-adrenoreceptors (ARs) …
Beta-3 adrenoceptors: A potential therapeutic target for heart disease
G Kayki-Mutlu, I Karaomerlioglu, E Arioglu-Inan… - European journal of …, 2019 - Elsevier
As heart failure (HF) is a growing public health problem worldwide, rapid therapeutic
development is required to improve HF management. Decreased myocardial contractility in …
development is required to improve HF management. Decreased myocardial contractility in …
Cardiac salvage by tweaking with beta-3-adrenergic receptors
JL Balligand - Cardiovascular research, 2016 - academic.oup.com
Overstimulation of the orthosympathetic system leads to cardiovascular cell and tissue
damage through prolonged activation of β-1-2 adrenergic receptors (BARs). The more …
damage through prolonged activation of β-1-2 adrenergic receptors (BARs). The more …
Beta-3 adrenoceptors as new therapeutic targets for cardiovascular pathologies
C Gauthier, B Rozec, B Manoury… - Current heart failure reports, 2011 - Springer
Catecholamines play a key role in the regulation of cardiovascular function, classically
through ß 1/2-adrenoreceptors (AR) activation. After ß 3-AR cloning in the late 1980s …
through ß 1/2-adrenoreceptors (AR) activation. After ß 3-AR cloning in the late 1980s …
β3-Adrenoceptors in the cardiovascular system: putative roles in human pathologies
B Rozec, C Gauthier - Pharmacology & therapeutics, 2006 - Elsevier
The sympathetic nervous system is central for the neurohumoral regulation of the
cardiovascular system and is largely involved in many cardiovascular diseases affecting …
cardiovascular system and is largely involved in many cardiovascular diseases affecting …
Beta 3 adrenoreceptors protect from hypertrophic remodelling through AMP‐activated protein kinase and autophagy
E Dubois‐Deruy, R Gelinas, C Beauloye… - ESC heart …, 2020 - Wiley Online Library
Aims The abundance of beta 3‐adrenergic receptors (β3‐ARs) is upregulated in diseased
human myocardium. We previously showed that cardiac‐specific expression of β3‐AR …
human myocardium. We previously showed that cardiac‐specific expression of β3‐AR …
Early and Delayed Consequences of β2-Adrenergic Receptor Overexpression in Mouse Hearts: Critical Role for Expression Level
SB Liggett, NM Tepe, JN Lorenz, AM Canning… - circulation, 2000 - Am Heart Assoc
Background—Transgenic cardiac β2-adrenergic receptor (AR) overexpression has resulted
in enhanced signaling and cardiac function in mice, whereas relatively low levels of …
in enhanced signaling and cardiac function in mice, whereas relatively low levels of …