Preorganization increases the self-assembling ability and antitumor efficacy of peptide nanomedicine
C Liang, Z Wang, T Xu, Y Chen, D Zheng… - … applied materials & …, 2020 - ACS Publications
Inspired by the biological process of phosphorylation for which different sites of the same
protein may have different activities and functions, we utilized phosphatase-based enzyme …
protein may have different activities and functions, we utilized phosphatase-based enzyme …
Enhanced cellular uptake and nuclear accumulation of drug-peptide nanomedicines prepared by enzyme-instructed self-assembly
C Liang, X Yan, R Zhang, T Xu, D Zheng, Z Tan… - Journal of Controlled …, 2020 - Elsevier
Subcellular delivery of nanomedicines has emerged as a promising approach to enhance
the therapeutic efficacy of anticancer drugs. Nuclear accumulation of anticancer drugs are …
the therapeutic efficacy of anticancer drugs. Nuclear accumulation of anticancer drugs are …
Spatiotemporal control of supramolecular self-assembly and function
The enzyme-triggered self-assembly of peptides has flourished in controlling the self-
assembly kinetics and producing nanostructures that are typically inaccessible by …
assembly kinetics and producing nanostructures that are typically inaccessible by …
Enzyme-instructed self-assembly of peptides containing phosphoserine to form supramolecular hydrogels as potential soft biomaterials
Enzyme-instructed self-assembly (EISA) offers a facile approach to explore the
supramolecular assemblies of small molecules in cellular milieu for a variety of biomedical …
supramolecular assemblies of small molecules in cellular milieu for a variety of biomedical …
Recent advance in tailoring the structure and functions of self-assembled peptide nanomaterials for biomedical applications
D Zhu, H Kong, Z Sun, Y Xu, P Han, Y Xi… - Coordination Chemistry …, 2023 - Elsevier
Molecular design and biomimetic/bioinspired synthesis provide facile ways for the
construction of functional nanomaterials for various applications. Peptide-based functional …
construction of functional nanomaterials for various applications. Peptide-based functional …
Enzyme‐instructed self‐assembly (EISA) and hydrogelation of peptides
J Gao, J Zhan, Z Yang - Advanced Materials, 2020 - Wiley Online Library
Self‐assembly is a powerful tool for constructing supramolecular materials for many
applications, ranging from energy harvesting to biomedicine. Among the methods to prepare …
applications, ranging from energy harvesting to biomedicine. Among the methods to prepare …
Enzyme-instructed peptide assembly favored by preorganization for cancer cell membrane engineering
Y Ding, D Zheng, L Xie, X Zhang, Z Zhang… - Journal of the …, 2023 - ACS Publications
Innovative methods for engineering cancer cell membranes promise to manipulate cell–cell
interactions and boost cell-based cancer therapeutics. Here, we illustrate an in situ …
interactions and boost cell-based cancer therapeutics. Here, we illustrate an in situ …
Self‐Assembling Proteins for Design of Anticancer Nanodrugs
Q Zou, R Chang, X Yan - Chemistry–An Asian Journal, 2020 - Wiley Online Library
Inspired by the diverse protein‐based structures and materials in organisms, proteins have
been expected as promising biological components for constructing nanomaterials toward …
been expected as promising biological components for constructing nanomaterials toward …
A comprehensive review on peptide-bearing biomaterials: From ex situ to in situ self-assembly
SY Qin, JQ Feng, YJ Cheng, WL Liu, AQ Zhang… - Coordination Chemistry …, 2024 - Elsevier
In the last few decades, we have witnessed the great advances of molecular self-assembly
in biomedical applications. Among the building blocks for molecular self-assembly, peptide …
in biomedical applications. Among the building blocks for molecular self-assembly, peptide …
Stimuli-controlled peptide self-assembly with secondary structure transitions and its application in drug release
Short peptides can self-assemble into supramolecular materials and be used for promising
biomedical applications. This area of research has seen tremendous development in recent …
biomedical applications. This area of research has seen tremendous development in recent …