Genetic susceptibility to aggressive prostate cancer

EA Ostrander, EM Kwon, JL Stanford - Cancer Epidemiology Biomarkers & …, 2006 - AACR
In 2006, f234, 460 men in the US will be diagnosed with prostate cancer, and> 27,000
deaths will be attributed to the disease (1). There is substantial phenotypic variability among …

Hereditary prostate cancer in African American families: linkage analysis using markers that map to five candidate susceptibility loci

WM Brown, EM Lange, H Chen, SL Zheng… - British journal of …, 2004 - nature.com
African American men have the highest incidence of prostate cancer in the world. Despite
this statistic, linkage studies designed to localise prostate cancer susceptibility alleles have …

Analysis of the prostate cancer–susceptibility locus HPC20 in 172 families affected by prostate cancer

CH Bock, JM Cunningham, SK McDonnell… - The American Journal of …, 2001 - cell.com
A recent study of hereditary prostate cancer has provided evidence for a prostate cancer–
susceptibility locus, HPC20, which maps to 20q13. To assess further the potential …

[PDF][PDF] Prostate cancer predisposition

Y Bhanji, WB Isaacs, J Xu, KA Cooney - Urologic Clinics of North America, 2021 - Elsevier
The three most important recognized risks for prostate cancer (PCa) are increasing age,
ancestry, and family history of the disease. The clustering of PCa within families can be …

Association of prostate cancer family history with histopathological and clinical characteristics of prostate tumors

E Spangler, CM Zeigler‐Johnson… - … journal of cancer, 2005 - Wiley Online Library
Genetic factors may be used not only to assess risk of prostate cancer development but also
to evaluate prostate cancer outcomes including clinical prognosis, treatment methods, and …

Prostate cancer: epidemiology and risk factors

JE Damber - Current Opinion in Urology, 1998 - journals.lww.com
After years of rapid increase, the incidence of prostate cancer has begun to decline in
certain areas in the USA. Although these temporal trends are consistent with the impact of …

Prostate cancer susceptibility genes: lessons learned and challenges posed.

J Simard, M Dumont, D Labuda… - Endocrine-related …, 2003 - erc.bioscientifica.com
In most developed countries, prostate cancer is the most frequently diagnosed malignancy
in men. The extent to which the marked racial/ethnic difference in its incidence rate is …

[HTML][HTML] Familial study of prostate cancer in Jamaica

FE Glover Jr, DS Coffey, LL Douglas, H Russell… - Urology, 1998 - Elsevier
Objectives. Rates of prostate cancer in Kingston, Jamaica are extremely high (occurring in
more than 300 men out of 100,000 in 1989 to 1993). This article addresses the familial …

Hereditary prostate cancer

JE Damber - Scandinavian Journal of Urology and Nephrology, 1999 - Taylor & Francis
Recent research makes it probable that there is a hereditary form of prostate cancer. By
identifying prostate cancer cases in the Swedish twin registry it was possible to show a …

Risk of cancer in relatives of prostate cancer probands

SD Isaacs, LALM Kiemeney… - JNCI: Journal of the …, 1995 - academic.oup.com
Background: It is estimated that there will be more than 244 000 new prostate cancer cases
diagnosed and that more than 40 000 men will die of this disease during 1995. Evidence …