[HTML][HTML] Intraoperative imaging-guided cancer surgery: from current fluorescence molecular imaging methods to future multi-modality imaging technology

C Chi, Y Du, J Ye, D Kou, J Qiu, J Wang, J Tian… - Theranostics, 2014 - ncbi.nlm.nih.gov
Cancer is a major threat to human health. Diagnosis and treatment using precision medicine
is expected to be an effective method for preventing the initiation and progression of cancer …

Regulatory aspects of optical methods and exogenous targets for cancer detection

WS Tummers, JM Warram, KE Tipirneni, J Fengler… - 2017 - AACR
Considerable advances in cancer-specific optical imaging have improved the precision of
tumor resection. In comparison to traditional imaging modalities, this technology is unique in …

[HTML][HTML] Optical image-guided surgery—where do we stand?

S Keereweer, JDF Kerrebijn, PBAA Van Driel… - Molecular Imaging and …, 2011 - Springer
In cancer surgery, intra-operative assessment of the tumor-free margin, which is critical for
the prognosis of the patient, relies on the visual appearance and palpation of the tumor …

Fluorescence guidance in surgical oncology: challenges, opportunities, and translation

MT Olson, QP Ly, AM Mohs - Molecular imaging and biology, 2019 - Springer
Surgical resection continues to function as the primary treatment option for most solid
tumors. However, the detection of cancerous tissue remains predominantly subjective and …

Real-time fluorescence image-guided oncologic surgery

SB Mondal, S Gao, N Zhu, R Liang, V Gruev… - Advances in cancer …, 2014 - Elsevier
Medical imaging plays a critical role in cancer diagnosis and planning. Many of these
patients rely on surgical intervention for curative outcomes. This requires a careful …

Fluorescent imaging of cancerous tissues for targeted surgery

L Bu, B Shen, Z Cheng - Advanced drug delivery reviews, 2014 - Elsevier
To maximize tumor excision and minimize collateral damage are the primary goals of cancer
surgery. Emerging molecular imaging techniques have made “image-guided surgery” …

[HTML][HTML] Intraoperative fluorescence molecular imaging accelerates the coming of precision surgery in China

Z Zhang, K He, C Chi, Z Hu, J Tian - European Journal of Nuclear Medicine …, 2022 - Springer
Purpose China has the largest cancer population globally. Surgery is the main choice for
most solid cancer patients. Intraoperative fluorescence molecular imaging (FMI) has shown …

Optical image-guided cancer surgery: challenges and limitations

S Keereweer, PBAA Van Driel, TJA Snoeks… - Clinical Cancer …, 2013 - AACR
Optical image-guided cancer surgery is a promising technique to adequately determine
tumor margins by tumor-specific targeting, potentially resulting in complete resection of …

Fundamentals and developments in fluorescence-guided cancer surgery

JSD Mieog, FB Achterberg, A Zlitni… - Nature reviews Clinical …, 2022 - nature.com
Fluorescence-guided surgery using tumour-targeted imaging agents has emerged over the
past decade as a promising and effective method of intraoperative cancer detection. An …

[HTML][HTML] Intraoperative molecular imaging clinical trials: a review of 2020 conference proceedings

F Azari, G Kennedy, E Bernstein… - … of biomedical optics, 2021 - spiedigitallibrary.org
Significance: Surgery is often paramount in the management of many solid organ
malignancies because optimal resection is a major factor in disease-specific survival …