Signaling pathways regulating red blood cell aggregation

A Muravyov, I Tikhomirova - Biorheology, 2014 - content.iospress.com
The exposure of red blood cells (RBC) to some hormones (epinephrine, insulin and
glucagon) and agonists of α-and β-adrenergic receptors (phenylephrine, clonidine and …

Red blood cell aggregation changes are depended on its initial value: Effect of long-term drug treatment and short-term cell incubation with drug

AV Muravyov, IA Tikhomirova… - Clinical …, 2011 - content.iospress.com
This study was designed to investigate whether the red cell aggregation depends on its
initial level under drug therapy or cell incubation with bioactive chemical compounds. Sixty …

Crosstalk between adenylyl cyclase signaling pathway and Ca 2+ regulatory mechanism under red blood cell microrheological changes

AV Muravyov, IA Tikhomirova… - Clinical …, 2010 - content.iospress.com
There are evidences that red blood cell (RBC) deformation and aggregation change under
their incubation with catecholamines and it is connected with activation of intracellular …

Extra-and intracellular signaling pathways under red blood cell aggregation and deformability changes

AV Muravyov, IA Tikhomirova… - Clinical …, 2009 - content.iospress.com
Exposure of red blood cells (RBCs) to catecholamines (epinephrine, phenylephrine, an
agonist of α 1-adrenergic receptors, clonidine, an agonist of α 2-adrenergic receptors and …

Role molecular signaling pathways in changes of red blood cell deformability

AV Muravyov, IA Tikhomirova - Clinical hemorheology and …, 2013 - content.iospress.com
This study was designed to investigate the dependency of the red blood cell deformability
upon activation of extra-and intracellular signaling pathways. Exposures of red blood cells …

Role Ca2+ in Mechanisms of the Red Blood Cells Microrheological Changes

A Muravyov, I Tikhomirova - Calcium signaling, 2012 - Springer
To assess the physiological role of intracellular Ca 2+ in the changes of microrheological
red blood cell (RBC) properties (RBC deformability and aggregation), we employed several …

Hemodynamic effects of red blood cell aggregation

OK Baskurt, HJ Meiselman - 2007 - nopr.niscpr.res.in
The influence of red blood cell (RBC) aggregation on blood flow in vivo has been under
debate since early 1900's, yet a full understanding has still has not been reached. Enhanced …

Red blood cell aggregation

B Neu, HJ Meiselman - BIOMEDICAL AND HEALTH RESEARCH …, 2007 - books.google.com
The reversible aggregation of human red blood cells (RBC) continues to be of interest in the
field of hemorheology [1-12], in that RBC aggregation is a major determinant of the in vitro …

Do physiological concentrations of IgG induce a direct aggregation of red blood cells: comparison with fibrinogen

L Game, JC Voegel, P Schaaf, JF Stoltz - Biochimica et Biophysica Acta …, 1996 - Elsevier
Under physiological conditions, red blood cells (RBCs) form aggregates that allow blood
flow in all the circulatory system. RBC aggregation is the result of local flow shear stress …

Increased ability of erythrocytes to aggregate in spontaneously hypertensive rats

D Lominadze, DA Schuschke, IG Joshua… - Clinical and …, 2002 - Taylor & Francis
The development of hypertension is accompanied by changes in the rheological properties
of blood, particularly by increased red blood cell (RBC) aggregation leading to further …