[HTML][HTML] Role of epigenetic alterations in the pathogenesis of Barrett's esophagus and esophageal adenocarcinoma

A Agarwal, R Polineni, Z Hussein, I Vigoda… - … journal of clinical and …, 2012 - ncbi.nlm.nih.gov
Barrett's esophagus, a pre-malignant condition that can lead to esophageal
adenocarcinoma, is characterized by histological changes in the normal squamous …

Genetic and epigenetic alterations in Barrett's esophagus and esophageal adenocarcinoma

AM Kaz, WM Grady, MD Stachler… - Gastroenterology …, 2015 - gastro.theclinics.com
Genetic and Epigenetic Alterations in Barrett’s Esophagus and Esophageal Adenocarcinoma -
Gastroenterology Clinics Skip to Main Content Skip to Main Menu Advertisement …

Epigenetic patterns in the progression of esophageal adenocarcinoma

CA Eads, RV Lord, K Wickramasinghe, TI Long… - Cancer research, 2001 - AACR
Esophageal adenocarcinoma (EAC) arises after normal squamous mucosa undergoes
metaplasia to specialized columnar epithelium (intestinal metaplasia or Barrett's …

DNA methylation profiling in Barrett's esophagus and esophageal adenocarcinoma reveals unique methylation signatures and molecular subclasses

AM Kaz, CJ Wong, Y Luo, JB Virgin, MK Washington… - Epigenetics, 2011 - Taylor & Francis
Barrett's esophagus (BE) is a metaplastic process whereby the normal stratified, squamous
esophageal epithelium is replaced by specialized intestinal epithelium. Barrett's is the only …

Recent developments in the molecular characterization of Barrett's esophagus

RC Fitzgerald, G Triadafilopoulos - Digestive Diseases, 1998 - karger.com
Barrett's esophagus, or specialized intestinal metaplasia, is a common condition associated
with gastroesophageal reflux and an increased risk for adenocarcinoma of the esophagus …

DNA methylation as an adjunct to histopathology to detect prevalent, inconspicuous dysplasia and early-stage neoplasia in Barrett's esophagus

MA Alvi, X Liu, M O'Donovan, R Newton… - Clinical Cancer …, 2013 - AACR
Abstract Purpose: Endoscopic surveillance of Barrett's esophagus is problematic because
dysplasia/early-stage neoplasia is frequently invisible and likely to be missed because of …

Similarity of aberrant DNA methylation in Barrett's esophagus and esophageal adenocarcinoma

E Smith, NJ De Young, SJ Pavey, NK Hayward… - Molecular cancer, 2008 - Springer
Background Barrett's esophagus (BE) is the metaplastic replacement of squamous with
columnar epithelium in the esophagus, as a result of reflux. It is the major risk factor for the …

Molecular evolution of metaplasia to adenocarcinoma in the esophagus

WM Grady, M Yu - Digestive diseases and sciences, 2018 - Springer
Esophageal adenocarcinoma (EAC) develops from Barrett's esophagus (BE), a condition
where the normal squamous epithelia is replaced by specialized intestinal metaplasia in …

The molecular biology of esophageal adenocarcinoma

LB Koppert, BPL Wijnhoven… - Journal of surgical …, 2005 - Wiley Online Library
Background Barrett's esophagus is an acquired metaplastic change that occurs in the distal
esophagus secondary to chronic gastroesophageal reflux. This premalignant condition …

The evolving genomic landscape of Barrett's esophagus and esophageal adenocarcinoma

G Contino, TL Vaughan, D Whiteman, RC Fitzgerald - Gastroenterology, 2017 - Elsevier
We have recently gained unprecedented insight into genetic factors that determine risk for
Barrett's esophagus (BE) and progression to esophageal adenocarcinoma (EA). Next …