Inulin Reduces Kidney Damage in Type 2 Diabetic Mice by Decreasing Inflammation and Serum Metabolomics

J He, X Li, M Yan, X Chen, C Sun, J Tan… - Journal of Diabetes …, 2024 - Wiley Online Library
This study is aimed at assessing the impact of soluble dietary fiber inulin on the treatment of
diabetes‐related chronic inflammation and kidney injury in mice with type 2 diabetes …

Dietary inulin alleviates diverse stages of type 2 diabetes mellitus via anti-inflammation and modulating gut microbiota in db/db mice

K Li, L Zhang, J Xue, X Yang, X Dong, L Sha, H Lei… - Food & function, 2019 - pubs.rsc.org
Type 2 diabetes mellitus (T2DM) is closely correlated with chronic low-grade inflammation
and gut dysbiosis. Prebiotic inulin (INU) is conducive to modulate gut dysbiosis. However …

Inulin ameliorates metabolic syndrome in high-fat diet-fed mice by regulating gut microbiota and bile acid excretion

S Huang, S Dong, L Lin, Q Ma, M Xu, L Ni… - Frontiers in …, 2023 - frontiersin.org
Background: Inulin is a natural plant extract that improves metabolic syndrome by
modulating the gut microbiota. Changes in the gut microbiota may affect intestinal bile acids …

[HTML][HTML] The combinational effect of inulin and resveratrol on the oxidative stress and inflammation level in a rat model of diabetic nephropathy

F Ghavidel, H Amiri, MH Tabrizi, S Alidadi… - Current Developments …, 2024 - Elsevier
Background Using inulin can enhance resveratrol's effects by improving the intestinal
microbiome and the stability of resveratrol. Objectives We aimed to investigate the effect of …

The Influence of Soy Isoflavones and Soy Isoflavones with Inulin on Kidney Morphology, Fatty Acids, and Associated Parameters in Rats with and without Induced …

K Misiakiewicz-Has… - International Journal of …, 2024 - mdpi.com
Diabetes mellitus resulting from hyperglycemia stands as the primary cause of diabetic
kidney disease. Emerging evidence suggests that plasma concentrations of soy isoflavones …

Inulin inhibits the inflammatory response through modulating enteric glial cell function in type 2 diabetic mellitus mice by reshaping intestinal flora

MY Li, JQ Duan, XH Wang, M Liu, QY Yang, Y Li… - ACS …, 2023 - ACS Publications
Inulin, a commonly used dietary fiber supplement, is capable of modulating the gut
microbiome. Chronic inflammation resulting from metabolic abnormalities and gut flora …

Dietary supplementation of inulin alleviates metabolism disorders in gestational diabetes mellitus mice via RENT/AKT/IRS/GLUT4 pathway

M Miao, Y Dai, C Rui, Y Fan, X Wang, C Fan… - Diabetology & Metabolic …, 2021 - Springer
Background Gestational diabetes mellitus (GDM) has significant short and long-term health
consequences for both the mother and child. There is limited but suggestive evidence that …

Effects of allicin on pathophysiological mechanisms during the progression of nephropathy associated to diabetes

AS Arellano-Buendía, LG Castañeda-Lara… - Antioxidants, 2020 - mdpi.com
This study aimed to assess the impact of allicin on the course of diabetic nephropathy. Study
groups included control, diabetes, and diabetes-treated rats. Allicin treatment (16 mg/kg …

[HTML][HTML] Inulin-type fructan improves diabetic phenotype and gut microbiota profiles in rats

Q Zhang, H Yu, X Xiao, L Hu, F Xin, X Yu - PeerJ, 2018 - peerj.com
Methods A diabetic rat model was generated by a high-fat diet and streptozotocin injections
(HF/STZ). Inulin was orally administered to normal and diabetic rats. To determine the …

Improvement of myocardial injury and gut microbiota disturbance in type 2 diabetic mice by inulin with various degrees of polymerization

S Jia, J Li, B Yu, M Li, B Cui - Food Bioscience, 2023 - Elsevier
This study is to explore the effects of low-performance inulin (SI, DP< 10) and high-
performance inulin (HI, DP> 10) on myocardial injury in type 2 diabetic mice fed a high-fat …