Secondhand smoke (SHS) has long been linked to lung cancer and other diseases in
nonsmokers. Yet, the underlying mechanisms of SHS carcinogenicity in nonsmokers remain …

Secondhand smoke (SHS) exposure is a known risk factor for lung cancer development in
lifelong nonsmokers; however, the mechanistic involvement of SHS in the genesis of this …

Exposure to thirdhand smoke (THS) is a recently described health concern that arises in
many indoor environments. However, the carcinogenic potential of THS, a critical …

Postgenomic methodologies have provided novel tools for evaluating safety and efficacy of
cancer chemopreventive agents. We exposed rats to environmental cigarette smoke (ECS) …

Cigarette smoke (CS) induces lung cancer through a multistep process that is now being
depicted by molecular analyses. During the early phase (weeks), DNA damage occurs in …

Objectives Secondhand smoke (SHS) is a major risk factor for lung cancer in nonsmokers.
DNA damage-derived mutagenicity is a well-established mechanism of SHS …

Cigarette smoke (CS) is known to cause cancer and other diseases, but little is known about
the global molecular and cellular changes that occur prior to the appearance of clinically …

The A/J mouse is highly susceptible to lung tumor induction and has been widely used as a
screening model in carcinogenicity testing and chemoprevention studies. However, the A/J …

Cigarette smoke plays a major role in the epidemiology of lung cancer, and smoke
components have extensively been investigated in carcinogenicity and chemoprevention …

Increasing evidence has shown that thirdhand smoke (THS) exposure is likely to induce
adverse health effects. An important knowledge gap remains in our understanding of THS …