Exposure of mice to secondhand smoke elicits both transient and long‐lasting transcriptional changes in cancer‐related functional networks
S Tommasi, A Zheng… - International journal of …, 2015 - Wiley Online Library
Secondhand smoke (SHS) has long been linked to lung cancer and other diseases in
nonsmokers. Yet, the underlying mechanisms of SHS carcinogenicity in nonsmokers remain …
nonsmokers. Yet, the underlying mechanisms of SHS carcinogenicity in nonsmokers remain …
New experimental data linking secondhand smoke exposure to lung cancer in nonsmokers
Secondhand smoke (SHS) exposure is a known risk factor for lung cancer development in
lifelong nonsmokers; however, the mechanistic involvement of SHS in the genesis of this …
lifelong nonsmokers; however, the mechanistic involvement of SHS in the genesis of this …
Short-term early exposure to thirdhand cigarette smoke increases lung cancer incidence in mice
B Hang, Y Wang, Y Huang, P Wang… - Clinical …, 2018 - portlandpress.com
Exposure to thirdhand smoke (THS) is a recently described health concern that arises in
many indoor environments. However, the carcinogenic potential of THS, a critical …
many indoor environments. However, the carcinogenic potential of THS, a critical …
Chemoprevention of genome, transcriptome, and proteome alterations induced by cigarette smoke in rat lung
A Izzotti, M Bagnasco, C Cartiglia, M Longobardi… - European journal of …, 2005 - Elsevier
Postgenomic methodologies have provided novel tools for evaluating safety and efficacy of
cancer chemopreventive agents. We exposed rats to environmental cigarette smoke (ECS) …
cancer chemopreventive agents. We exposed rats to environmental cigarette smoke (ECS) …
Molecular damage and lung tumors in cigarette smoke–exposed mice
A Izzotti, A Pulliero - Annals of the New York Academy of …, 2015 - Wiley Online Library
Cigarette smoke (CS) induces lung cancer through a multistep process that is now being
depicted by molecular analyses. During the early phase (weeks), DNA damage occurs in …
depicted by molecular analyses. During the early phase (weeks), DNA damage occurs in …
Expression of epigenetic modifiers is not significantly altered by exposure to secondhand smoke
S Tommasi, A Zheng, A Besaratinia - Lung Cancer, 2015 - Elsevier
Objectives Secondhand smoke (SHS) is a major risk factor for lung cancer in nonsmokers.
DNA damage-derived mutagenicity is a well-established mechanism of SHS …
DNA damage-derived mutagenicity is a well-established mechanism of SHS …
Gene expression profiling in respiratory tissues from rats exposed to mainstream cigarette smoke
S Gebel, B Gerstmayer, A Bosio… - …, 2004 - academic.oup.com
Cigarette smoke (CS) is known to cause cancer and other diseases, but little is known about
the global molecular and cellular changes that occur prior to the appearance of clinically …
the global molecular and cellular changes that occur prior to the appearance of clinically …
Systems toxicology approaches enable mechanistic comparison of spontaneous and cigarette smoke-related lung tumor development in the A/J mouse model
K Luettich, Y Xiang, A Iskandar, A Sewer… - Interdisciplinary …, 2014 - sciendo.com
The A/J mouse is highly susceptible to lung tumor induction and has been widely used as a
screening model in carcinogenicity testing and chemoprevention studies. However, the A/J …
screening model in carcinogenicity testing and chemoprevention studies. However, the A/J …
Induction and modulation of lung tumors: genomic and transcriptional alterations in cigarette smoke-exposed mice
S De Flora, A Izzotti, F D'Agostini… - Experimental lung …, 2004 - Taylor & Francis
Cigarette smoke plays a major role in the epidemiology of lung cancer, and smoke
components have extensively been investigated in carcinogenicity and chemoprevention …
components have extensively been investigated in carcinogenicity and chemoprevention …
Thirdhand tobacco smoke exposure increases the genetic background-dependent risk of pan-tumor development in Collaborative Cross mice
H Yang, X Wang, P Wang, L He, SF Schick… - Environment …, 2023 - Elsevier
Increasing evidence has shown that thirdhand smoke (THS) exposure is likely to induce
adverse health effects. An important knowledge gap remains in our understanding of THS …
adverse health effects. An important knowledge gap remains in our understanding of THS …
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