Perioperative application of somatostatin analogs for pancreatic surgery—current status in Germany

A Volk, P Nitschke, F Johnscher, N Rahbari… - … archives of surgery, 2016 - Springer
Background The most common major complication after pancreatic resection is the
postoperative pancreatic fistula (POPF). Somatostatin analogs can reduce POPF, but the …

[HTML][HTML] Meta-analysis of randomized controlled trials on the effectiveness of somatostatin analogues for pancreatic surgery: a Cochrane review

RS Koti, KS Gurusamy, G Fusai, BR Davidson - Hpb, 2010 - Elsevier
Background The use of synthetic analogues of somatostatin following pancreatic surgery is
controversial. The aim of this meta-analysis is to determine whether prophylactic …

The effect of somatostatin analogues on postoperative outcomes following pancreatic surgery: A meta-analysis

X Han, Z Xu, S Cao, Y Zhao, W Wu - PLoS One, 2017 - journals.plos.org
Background Leakage from the pancreatic stump is a leading cause of morbidity following
pancreatic surgery. It is essential to evaluate the effect of somatostatin analogues (SAs) …

Meta-analysis of the value of somatostatin and its analogues in reducing complications associated with pancreatic surgery

S Connor, N Alexakis, OJ Garden… - Journal of British …, 2005 - academic.oup.com
Background The role of somatostatin and its analogues in reducing complications after
pancreatic resection is controversial. This is a meta-analysis of the evidence of benefit …

Somatostatin analogues for pancreatic surgery

KS Gurusamy, R Koti, G Fusai… - Cochrane database …, 1996 - cochranelibrary.com
Background Pancreatic resections are associated with high morbidity (30% to 60%) and
mortality (5%). Synthetic analogues of somatostatin are advocated by some surgeons to …

Efficacy of somatostatin and its analogues in prevention of postoperative complications after pancreaticoduodenectomy: a meta-analysis of randomized controlled …

Q Zeng, Q Zhang, S Han, Z Yu, M Zheng, M Zhou… - Pancreas, 2008 - journals.lww.com
Objective: The aim of this study was to evaluate the efficacy of somatostatin and its
analogues in prevention of postoperative complications after pancreaticoduodenectomy …

Do somatostatin-analogues have the same impact on postoperative morbidity and pancreatic fistula in patients after pancreaticoduodenectomy and distal …

S Schorn, T Vogel, IE Demir, E Demir, O Safak… - Pancreatology, 2020 - Elsevier
Objective Postoperative pancreatic fistula/POPF is the most feared complication in
pancreatic surgery. Although several systematic reviews investigated the impact of …

Systematic review and meta-analysis of somatostatin analogues in the prevention of postoperative complication after pancreaticoduodenectomy

K Jin, H Zhou, J Zhang, W Wang, Y Sun, C Ruan… - Digestive …, 2015 - karger.com
Background: The use of somatostatin analogues (SAs) following pancreaticoduodenectomy
(PD) is controversial. Method: Literature databases were searched systematically for …

Clinical evaluation of somatostatin use in pancreatic resections: Clinical efficacy or limited benefit?

RJ Anderson, E Dunki-Jacobs, GG Callender… - Surgery, 2013 - Elsevier
Background The benefit of somatostatin for the prevention of pancreatic fistula has been
debated widely in the literature. The aim of this study was to evaluate the efficacy of …

[HTML][HTML] Somatostatin analogues for the prevention of pancreatic fistula after open pancreatoduodenectomy: A nationwide analysis

BT Bootsma, VD Plat, T van de Brug, DE Huisman… - Pancreatology, 2022 - Elsevier
Background Somatostatin analogues (SA) are currently used to prevent postoperative
pancreatic fistula (POPF) development. However, its use is controversial. This study …