Drug-related exanthema under immunotherapy and targeted oncological therapy

M Ziemer, E Livingstone - Dermatologie (Heidelberg, Germany), 2024 - europepmc.org
Background Oncological therapies can cause a variety of mucocutaneous adverse events.
Exanthematous adverse events can be challenging in the context of the urgent need for …

Drug eruptions with novel targeted therapies–immune checkpoint and EGFR inhibitors

I Pospischil, W Hoetzenecker - JDDG: Journal der Deutschen …, 2021 - Wiley Online Library
Given the increasing use of novel targeted therapies, dermatologists are constantly
confronted with novel cutaneous side effects of these agents. A rapid diagnosis and …

[HTML][HTML] Dermatologic immune-related adverse events: The toxicity spectrum and recommendations for management

Z Apalla, B Rapoport, V Sibaud - International journal of women's …, 2021 - Elsevier
Immune checkpoint inhibitors are a new class of oncologic drugs that act via the inhibition of
checkpoints, thereby unlocking the immune system to attack cancer cells. Their emergence …

Drug reactions with eosinophilia and systemic symptoms induced by immune checkpoint inhibitors: an international cohort of 13 cases

S Ingen-Housz-Oro, B Milpied, B Bensaid… - Melanoma …, 2023 - journals.lww.com
Among dermatologic adverse events induced by immune checkpoint inhibitors (ICI), drug
reactions with eosinophilia and systemic symptoms (DRESS) have been very rarely …

Dermatological side effects of immunotherapy drugs and targeted cancer therapies: Importance of dermatology and oncology collaboration

U Çelik, EH Aydemir, B Engin, MÇ Oba… - Journal of Oncology …, 2021 - journals.sagepub.com
Introduction Novel anti-cancer drugs such as targeted cancer therapies and immune check-
point inhibitors (ICIs) have adverse events, especially concerning the skin. The aim of this …

Systemic treatment of cutaneous adverse events after immune checkpoint inhibitor therapy: A review

AM Brown, W Masterson, J Lo, AB Patel - Dermatitis®, 2023 - liebertpub.com
As treatment with immune checkpoint inhibitors (CPIs) for cancer increases, so has the
incidence of immune-related cutaneous adverse events (irCAEs). These toxicities can …

Clinical Features and Management of Dermatologic Immune-Related Adverse Events for the Inpatient Dermatologist

CJ Fay, C Iriarte, BS Allais, CE Pisano, A Jfri… - Current Dermatology …, 2023 - Springer
Abstract Purpose of Review Immune checkpoint inhibitors (ICIs) have become a mainstay of
oncologic treatment over the past decade. There are currently 11 ICIs approved by the US …

Immunotherapy-mediated dermatological adverse events: the urgent need for a common, clinically meaningful, management strategy

Z Apalla, V Sibaud - Supportive Care in Cancer, 2020 - Springer
The introduction of immune checkpoint inhibitors as a treatment modality in advanced
malignancies has revolutionized the field of oncology therapeutics. Immunotherapy …

Cutaneous hypersensitivity reactions to immune checkpoint inhibitors

R Storgard, A Markova - The Journal of Allergy and Clinical Immunology: In …, 2024 - Elsevier
The introduction of immune checkpoint inhibitors (ICIs) has transformed the management of
various malignancies. Alongside their therapeutic success, the widespread application of …

Skin Adverse Reactions from New Cancer Immunotherapy

K Kerl, H Kerl, L Heinzerling - New and Emerging Entities in Dermatology …, 2021 - Springer
This chapter focuses on the broad side effect profile that can impact the skin in cancer
patients treated with checkpoint inhibitors. Special features include the clinical …