The strengths of scanning electron microscopy in deciphering SARS-CoV-2 infectious cycle
D Brahim Belhaouari, A Fontanini, JP Baudoin… - Frontiers in …, 2020 - frontiersin.org
Electron microscopy is a powerful tool in the field of microbiology. It has played a key role in
the rapid diagnosis of viruses in patient samples and has contributed significantly to the …
the rapid diagnosis of viruses in patient samples and has contributed significantly to the …
SIM imaging resolves endocytosis of SARS-CoV-2 spike RBD in living cells
L Miao, C Yan, Y Chen, W Zhou, X Zhou, Q Qiao… - Cell chemical …, 2023 - cell.com
It is urgent to understand the infection mechanism of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) for the prevention and treatment of COVID-19. The infection of …
coronavirus 2 (SARS-CoV-2) for the prevention and treatment of COVID-19. The infection of …
Correlative multi-scale cryo-imaging unveils SARS-CoV-2 assembly and egress
Since the outbreak of the SARS-CoV-2 pandemic, there have been intense structural studies
on purified viral components and inactivated viruses. However, structural and ultrastructural …
on purified viral components and inactivated viruses. However, structural and ultrastructural …
Genomic RNA elements drive phase separation of the SARS-CoV-2 nucleocapsid
C Iserman, CA Roden, MA Boerneke, RSG Sealfon… - Molecular cell, 2020 - cell.com
We report that the SARS-CoV-2 nucleocapsid protein (N-protein) undergoes liquid-liquid
phase separation (LLPS) with viral RNA. N-protein condenses with specific RNA genomic …
phase separation (LLPS) with viral RNA. N-protein condenses with specific RNA genomic …
[HTML][HTML] Crystal structure of SARS-CoV-2 nucleocapsid protein RNA binding domain reveals potential unique drug targeting sites
S Kang, M Yang, Z Hong, L Zhang, Z Huang… - … Pharmaceutica Sinica B, 2020 - Elsevier
The outbreak of coronavirus disease (COVID-19) caused by SARS-CoV-2 virus continually
lead to worldwide human infections and deaths. Currently, there is no specific viral protein …
lead to worldwide human infections and deaths. Currently, there is no specific viral protein …
Understanding individual SARS-CoV-2 proteins for targeted drug development against COVID-19
J van de Leemput, Z Han - Molecular and cellular biology, 2021 - Taylor & Francis
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of the COVID-
19 pandemic, responsible for millions of deaths globally. Even with effective vaccines, SARS …
19 pandemic, responsible for millions of deaths globally. Even with effective vaccines, SARS …
SARS-CoV-2 biology and host interactions
S Steiner, A Kratzel, GT Barut, RM Lang… - Nature Reviews …, 2024 - nature.com
The zoonotic emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
and the ensuing coronavirus disease 2019 (COVID-19) pandemic have profoundly affected …
and the ensuing coronavirus disease 2019 (COVID-19) pandemic have profoundly affected …
Ultrastructural analysis of SARS-CoV-2 interactions with the host cell via high resolution scanning electron microscopy
SARS-CoV-2 is the cause of the ongoing COVID-19 pandemic. Here, we investigated the
interaction of this new coronavirus with Vero cells using high resolution scanning electron …
interaction of this new coronavirus with Vero cells using high resolution scanning electron …
[HTML][HTML] SARS-CoV-2 spike D614G variant confers enhanced replication and transmissibility
During the evolution of SARS-CoV-2 in humans a D614G substitution in the spike (S) protein
emerged and became the predominant circulating variant (S-614G) of the COVID-19 …
emerged and became the predominant circulating variant (S-614G) of the COVID-19 …
The role of SARS-CoV-2 nucleocapsid protein in antiviral immunity and vaccine development
H Yu, F Guan, H Miller, J Lei, C Liu - Emerging microbes & …, 2023 - Taylor & Francis
ABSTRACT The coronavirus disease 2019 (COVID-19) has caused enormous health risks
and global economic disruption. This disease is caused by the severe acute respiratory …
and global economic disruption. This disease is caused by the severe acute respiratory …