Mandatory contrast-enhanced venography to detect deep-vein thrombosis (DVT) in studies of DVT prophylaxis: upsides and downsides

J Hirsh, JS Ginsberg, N Chan, G Guyatt… - Thrombosis and …, 2014 - thieme-connect.com
The introduction of venography into patient care was a major advance because it was the
first accurate method for the diagnosis of DVT. Compression ultrasound has since become …

End points in studies on the prevention of deep vein thrombosis

F Sonaglia, R Rossi, G Agnelli - Seminars in thrombosis and …, 2001 - thieme-connect.com
Clinically overt events are of obvious relevance for the outcome of patients. There is
unanimous consensus of clinicians that these events should be prevented in clinical …

The assessment of deep vein thromboses for therapeutic trials

A Leizorovicz, B Kassai, F Becker, M Cucherat - Angiology, 2003 - journals.sagepub.com
In the current paper, we provide recommendations for the assessment of deep vein throm
boses for the purpose of therapeutic trials evaluating antithrombotic drugs in the prevention …

Lack of consistency in the relationship between asymptomatic DVT detected by venography and symptomatic VTE in thromboprophylaxis trials

NC Chan, AC Stehouwer, J Hirsh… - Thrombosis and …, 2015 - thieme-connect.com
Asymptomatic deep-vein thrombosis (DVT) detected by mandatory venography, a surrogate
outcome, comprises most of the efficacy outcome events in recent thromboprophylaxis trials …

Clinical trials of deep vein thrombosis prophylaxis in medical patients

W Ageno, AGG Turpie - Clinical Cornerstone, 2005 - Elsevier
Autopsies and clinical studies have shown that venous thromboembolism (VTE) is a
common cause of morbidity and mortality in medical patients. Prophylaxis of VTE has been …

Asymptomatic patients at high risk for deep venous thrombosis who receive inadequate prophylaxis should be screened.

CA Estrada, J McElligott, JM Dolezal… - Southern medical …, 1999 - europepmc.org
Background Patients after stroke and major orthopedic surgery have increased factors for
developing deep vein thrombosis. We sought to determine the implications of screening …

Safety of venous ultrasound in suspected DVT–still a matter of concern?

J Beyer-Westendorf - Thrombosis and haemostasis, 2009 - thieme-connect.com
Although venous ultrasound has been introduced into clini-cal practice more than 20 years
ago there is ongoing debate about accuracy, reproducibility and the best scanning protocol …

Current role of venography in the diagnosis of deep-vein thrombosis.

R Rossi, G Agnelli - Minerva cardioangiologica, 1998 - europepmc.org
The clinical diagnosis of deep vein thrombosis (DVT) is barely sensitive and specific. Thus,
the clinical suspicion of DVT needs to be confirmed by objective testing. Venography has …

Benefits of deep-vein thrombosis prophylaxis in the nonsurgical patient: The MEDENOX trial

AT Cohen, HM Zaw, R Alikhan - Seminars in hematology, 2001 - Elsevier
Venous thromboembolism (VTE) is a common complication of hospitalized patients,
imposing a major clinical and economic burden. Three of four cases of fatal pulmonary …

Residual thrombosis on ultrasonography to guide the duration of anticoagulation in patients with deep venous thrombosis: a randomized trial

P Prandoni, MH Prins, AWA Lensing… - Annals of internal …, 2009 - acpjournals.org
Background: The optimal duration of oral anticoagulant therapy in patients with deep venous
thrombosis (DVT) of the lower extremities remains uncertain. Objective: To assess whether …