Molecular profiling in sarcoidosis

NK Arger, B O'Connor, LL Koth - Current opinion in pulmonary …, 2020 - journals.lww.com
While the molecular profiling studies to date offer the ability to compare sarcoidosis and
health as well as across tissues, further longitudinal studies that include sarcoidosis patients …

Functional genomics and prognosis in sarcoidosis--the critical role of antigen presentation.

RM Rutherford, F Staedtler, J Kehren… - … vasculitis, and diffuse …, 2004 - europepmc.org
Background Sarcoidosis is a systemic disorder of unknown cause, highly variable
phenotype and unpredictable outcome. Antigen processing, inflammatory response and …

Sarcoidosis news: immunologic frontiers for new immunosuppressive strategies

C Agostini, U Costabel, G Semenzato - Clinical immunology and …, 1998 - Elsevier
Although the etiology of sarcoidosis is still unknown, it is now clear that the formation of the
sarcoid granuloma is keenly regulated by a cascade of cytokines. Furthermore, several …

Sarcoidosis and autoimmunity

M Song, M Manansala, PJ Parmar… - Current Opinion in …, 2021 - journals.lww.com
Advancements in the understanding of sarcoidosis support its consideration as an
autoimmune disease. Sarcoidosis patients carry a higher risk of comorbid autoimmune …

[HTML][HTML] Current perspectives on the immunopathogenesis of sarcoidosis

S Lee, D Birnie, G Dwivedi - Respiratory Medicine, 2020 - Elsevier
Sarcoidosis is an inflammatory systemic disease that commonly affects the lungs or lymph
nodes but can manifest in other organs. Herein, we review the latest evidence establishing …

Immunogenetics of disease-causing inflammation in sarcoidosis

J Grunewald, P Spagnolo, J Wahlström… - Clinical reviews in allergy …, 2015 - Springer
Sarcoidosis is a systemic inflammatory disorder characterised by tissue infiltration by
mononuclear phagocytes and lymphocytes with associated non-caseating granuloma …

Innate immunity in sarcoidosis pathobiology

ES Chen - Current opinion in pulmonary medicine, 2016 - journals.lww.com
Innate immunity in sarcoidosis pathobiology : Current Opinion in Pulmonary Medicine Innate
immunity in sarcoidosis pathobiology : Current Opinion in Pulmonary Medicine Log in or …

Cellular players in the immunopathogenesis of sarcoidosis

G Zissel, J Müller-Quernheim - Clinics in chest medicine, 2015 - chestmed.theclinics.com
Every year the knowledge on mediators, receptors, and, during the last years, on genes
possibly involved in sarcoidosis is growing. Nevertheless, its cause, its large variability, and …

The pathogenesis of pulmonary sarcoidosis and implications for treatment

KC Patterson, ES Chen - Chest, 2018 - Elsevier
Thoracic sarcoidosis is the most common form of sarcoidosis, encompassing a
heterogeneous group of patients with a wide range of clinical features and associated …

Inflammatory pathways in sarcoidosis

BP Barna, MA Judson, MJ Thomassen - … in Health and Disease, Volume II, 2021 - Springer
Abstract Concepts regarding etiology and pathophysiology of sarcoidosis have changed
remarkably within the past 5 years. Sarcoidosis is now viewed as a complex multi-causation …