Future directions in sarcoidosis research: summary of an NHLBI working group

WJ Martin, MC Iannuzzi, DB Gail… - American journal of …, 2004 - atsjournals.org
Sarcoidosis is a systemic granulomatous disease of unknown etiology that primarily affects
the lungs. The etiology remains unclear; however, environmental, genetic, ethnic, and …

Clinical presentations, pathogenesis, and therapy of sarcoidosis: state of the art

F Polverino, E Balestro, P Spagnolo - Journal of clinical medicine, 2020 - mdpi.com
Sarcoidosis is a systemic disease of unknown etiology characterized by the presence of
noncaseating granulomas that can occur in any organ, most commonly the lungs. Early and …

Immune mechanisms in fibrotic pulmonary sarcoidosis

P Weeratunga, DR Moller, LP Ho - European Respiratory …, 2022 - Eur Respiratory Soc
Sarcoidosis is an immune-mediated disorder. Its immunopathology has been steadily
mapped out over the past few decades. Despite this, the underpinning mechanisms for …

Emerging insights in sarcoidosis: moving forward through reverse translational research

A Liu, L Sharma, X Yan, CSD Cruz… - American Journal of …, 2022 - journals.physiology.org
Sarcoidosis is a chronic granulomatous disease of unknown etiology that primarily affects
the lungs. The development of stage IV or fibrotic lung disease accounts for a significant …

Etiology and immunopathogenesis of sarcoidosis: novel insights

E Beijer, M Veltkamp, B Meek… - Seminars in Respiratory …, 2017 - thieme-connect.com
Sarcoidosis is a disorder of unknown etiology. It is a systemic disease, frequently involving
the lungs, skin, eyes, and lymph nodes. It is characterized by formation of noncaseating …

Biomarkers in sarcoidosis: a review

H Ahmadzai, W Sheng Joshua Loke… - Current Biomarker …, 2014 - Taylor & Francis
Sarcoidosis is a systemic granulomatous disease of undetermined etiology invariably
affecting the lungs and thoracic lymph nodes. It has been termed an “immune paradox”, as …

Circulating cytokines in sarcoidosis: phenotype-specific alterations for fibrotic and non-fibrotic pulmonary disease

KC Patterson, BS Franek, J Müller-Quernheim… - Cytokine, 2013 - Elsevier
AIMS: Sarcoidosis is a granulomatous disease of unknown etiology marked by tremendous
clinical heterogeneity. Many patients enter remission with good long-term outcomes. Yet …

Genetic, immunologic, and environmental basis of sarcoidosis

DR Moller, BA Rybicki, NY Hamzeh… - Annals of the …, 2017 - atsjournals.org
Sarcoidosis is a multisystem disease with tremendous heterogeneity in disease
manifestations, severity, and clinical course that varies among different ethnic and racial …

The challenge of sarcoidosis

LS Efferen - Chest, 2001 - journal.chestnet.org
It is well-recognized that sarcoidosis is a multisystemic disorder of unknown etiology that can
present with a myriad of signs and symptoms, but most commonly presents with pulmonary …

Immunologic response of sarcoidosis

G Zissel, A Prasse… - Seminars in respiratory …, 2010 - thieme-connect.com
Sarcoidosis is a chronic granulomatous disorder characterized by an accumulation of T
lymphocytes, macrophages, and immune-effector cells within affected organs. The …