Immunological pathways in sarcoidosis and autoimmune rheumatic disorders—similarities and differences in an Italian prospective real-life preliminary study

M d'Alessandro, L Bergantini, S Gangi, E Conticini… - Biomedicines, 2023 - mdpi.com
Background: The pathogenesis of sarcoidosis involves T cells and B lymphocytes that
produce autoantibodies. We compared the expression of different T and B cell subsets in …

Clinical phenotypes in sarcoidosis

CAC Pereira, MC Dornfeld, R Baughman… - Current opinion in …, 2014 - journals.lww.com
Clinical phenotypes, by examining relationships between several domains in sarcoidosis,
are likely to better delineate the underlying processes and pathways. Larger studies with …

The clinical and immunologic features of pulmonary fibrosis in sarcoidosis

KC Patterson, K Hogarth, AN Husain, AI Sperling… - Translational …, 2012 - Elsevier
Sarcoidosis is a multisystem, granulomatous disease that most often affects the lungs. The
clinical course is highly variable; many patients undergo spontaneous remission, but up to a …

Immune response biomarkers as indicators of sarcoidosis presence, prognosis, and possible treatment: an immunopathogenic perspective

A Tarasidis, S Arce - Autoimmunity Reviews, 2020 - Elsevier
Sarcoidosis has been a disease of puzzling occurrence and clinical course. Multiple
immunological markers have been noted to be altered within sarcoidosis, however there is …

Potential immunotherapies for sarcoidosis

V Le, ED Crouser - Expert opinion on biological therapy, 2018 - Taylor & Francis
Introduction: Sarcoidosis is a chronic granulomatous inflammatory disease that commonly
causes lung disease, but can affect other vital organs and tissues. The cause of sarcoidosis …

Innate pathways shape sarcoidosis signaling: from bugs to drugs

ES Chen, ES White - American journal of respiratory and critical …, 2011 - atsjournals.org
Sarcoidosis is a granulomatous inflammatory disorder, primarily affecting the lungs, first
described by Sir Jonathan Hutchinson in 1877 (1). Since that time, clinicians and …

[PDF][PDF] New updates in sarcoidosis research: defining and renewing the quest

CA Bonham, M Sharp - American Journal of Physiology …, 2024 - journals.physiology.org
Sarcoidosis is a multisystem granulomatous disease with many unsolved mysteries,
including its cause 8 and cure (1). The heterogeneity of sarcoidosis, including multisystemic …

Advance in pathogenesis of sarcoidosis: Triggers and progression

C Chen, N Luo, F Dai, W Zhou, X Wu, J Zhang - Heliyon, 2024 - cell.com
Sarcoidosis, a multisystemic immune disease, significantly impacts patients' quality of life.
The complexity and diversity of its pathogenesis, coupled with limited comprehensive …

[PDF][PDF] Immunology and pathophysiology

G Semenzato, M Bortoli, E Brunetta… - EUROPEAN …, 2005 - ildcare.nl
Sarcoidosis is considered the archetype of immune granulomatous disorders, since
immunoregulatory mechanisms that play a part in the development of the sarcoid granuloma …

Key players and biomarkers of the adaptive immune system in the pathogenesis of sarcoidosis

ER Zhou, S Arce - International Journal of Molecular Sciences, 2020 - mdpi.com
Sarcoidosis is a systemic inflammatory disease characterized by development of
granulomas in the affected organs. Sarcoidosis is often a diagnosis of exclusion, and …