Potential use of biomarkers for the clinical evaluation of sarcoidosis
A Mousapasandi, C Herbert… - Journal of Investigative …, 2021 - journals.sagepub.com
Sarcoidosis is a systemic granulomatous disease of unknown etiology and pathogenesis
with a heterogeneous clinical presentation. In the appropriate clinical and radiological …
with a heterogeneous clinical presentation. In the appropriate clinical and radiological …
[HTML][HTML] Big data in sarcoidosis
NV Rivera - Current Opinion in Pulmonary Medicine - journals.lww.com
Sarcoidosis presents a complex challenge due to its unknown cause and heterogeneous
clinical manifestations. Collaborative networks, comprehensive phenotype delineation, and …
clinical manifestations. Collaborative networks, comprehensive phenotype delineation, and …
Identification of immune-relevant factors conferring sarcoidosis genetic risk
A Fischer, D Ellinghaus, M Nutsua… - American journal of …, 2015 - atsjournals.org
Rationale: Genetic variation plays a significant role in the etiology of sarcoidosis. However,
only a small fraction of its heritability has been explained so far. Objectives: To define further …
only a small fraction of its heritability has been explained so far. Objectives: To define further …
Defining CD4 T helper and T regulatory cell endotypes of progressive and remitting pulmonary sarcoidosis (BRITE): protocol for a US-based, multicentre, longitudinal …
LL Koth, LD Harmacek, EK White, NK Arger… - BMJ open, 2021 - bmjopen.bmj.com
Introduction Sarcoidosis is a multiorgan granulomatous disorder thought to be triggered and
influenced by gene–environment interactions. Sarcoidosis affects 45–300/100 000 …
influenced by gene–environment interactions. Sarcoidosis affects 45–300/100 000 …
Sarcoidosis-immunopathogenetic concepts
Sarcoidosis is a chronic granulomatous disorder characterized by an accumulation of
activated lymphocytes, predominantly T helper cells, expressing the Th1 phenotype and …
activated lymphocytes, predominantly T helper cells, expressing the Th1 phenotype and …
Adaptive immune system in pulmonary sarcoidosis—Comparison of peripheral and alveolar biomarkers
Sarcoidosis is a multi-systemic granulomatous disease of unknown origin. Recent research
has focused upon the role of autoimmunity in its development and progression. This study …
has focused upon the role of autoimmunity in its development and progression. This study …
Specific antigen (s) in sarcoidosis: a link to autoimmunity?
G Zissel, J Müller-Quernheim - European Respiratory Journal, 2016 - Eur Respiratory Soc
Pulmonary sarcoidosis is a systemic granulomatous disease of unknown origin
characterised by an increase in immune cells in the lower respiratory tract, mainly …
characterised by an increase in immune cells in the lower respiratory tract, mainly …
Immunopathogenesis of sarcoidosis
A Noor, KS Knox - Clinics in dermatology, 2007 - Elsevier
The immunopathogenesis of sarcoidosis has been difficult to charaterize given the
heterogeneity of disease, the elusiveness of the causative antigen, and the lack of an …
heterogeneity of disease, the elusiveness of the causative antigen, and the lack of an …
Clinical presentation and treatment of high-risk sarcoidosis
DM Perlman, MT Sudheendra, Y Furuya… - Annals of the …, 2021 - atsjournals.org
Sarcoidosis is a multisystem disease of unknown cause with heterogeneous clinical
manifestations and variable course. Spontaneous remissions occur in some patients …
manifestations and variable course. Spontaneous remissions occur in some patients …
[HTML][HTML] Biomarkers and molecular endotypes of sarcoidosis: lessons from omics and non-omics studies
Sarcoidosis is a chronic granulomatous disorder characterized by unknown etiology,
undetermined mechanisms, and non-specific therapies except TNF blockade. To improve …
undetermined mechanisms, and non-specific therapies except TNF blockade. To improve …