The interstitial space of the myocardium is composed of nonmyocyte cells and a highly
organized collagen network which serves to maintain the architecture and mechanical …

The cardiac interstitium is composed of non-myocyte cells embedded in a highly organized
extracellular matrix containing a three-dimensional collagen network which serves to …

The cardiac interstitium is composed of non-myocyte cells and a structural fibrillar protein
network which plays a dominant role in governing the structure, architecture, and …

Background Left ventricular hypertrophy is an adaptive process to increased loading of the
left ventricle. This condition becomes pathologic with impaired myocardial function if the …

Extrahepatic synthesis and localization of angiotensinogen have been described in animals,
thus establishing the tissue, renin-angiotensin system. We examined angiotensinogen …

In chronic heart failure, the inter-relationship of the renin-angiotensin-aldosterone system
(RAAS) and cardiac growth is of primary clinical interest. In the pressure or volume …

In hypertensive heart disease, after myocardial infarction or in congestive heart failure,
myocardial fibrosis presenting as a diffuse perivascular and interstitial accumulation of …

See article by Bishop et al.[26](pages 57–67) in this pacing in dogs, were associated with
activation of RAAS issue. and progressive increase in preload. There, myocardial fibrosis …

The interaction of the renin-angiotensin-aldosterone system (RAAS) and cardiac growth is of
great interest in chronic heart failure. The pressure or volume overloaded heart shows a …

A collagen network, composed largely of type I and III fibrillar collagens, is found in the
extracellular space of the myocardium. This network has multiple functions which includes a …