[HTML][HTML] Estrogen signaling via estrogen receptor β

C Zhao, K Dahlman-Wright, JÅ Gustafsson - Journal of Biological Chemistry, 2010 - ASBMB
Estrogens act by binding to and activating two estrogen receptors (ERs), ERα and ERβ.
Transcriptional regulation by ERs is controlled by a complex array of factors such as ER …

[HTML][HTML] Estrogen signaling: a subtle balance between ERα and ERβ

J Matthews, JÅ Gustafsson - Molecular interventions, 2003 - triggered.edina.clockss.org
The biological actions of estrogens are mediated by estrogen binding to one of two specific
estrogen receptors (ERs) ERα and ERβ, which belong to the nuclear receptor superfamily, a …

Regulation of estrogen receptor beta activity and implications in health and disease

E Swedenborg, KA Power, W Cai, I Pongratz… - Cellular and Molecular …, 2009 - Springer
Together with the estrogen receptor (ER) alpha, estrogen receptor beta (ERβ) mediates
many of the physiological effects of estrogens. As ERβ is crucially involved in a variety of …

Estrogen receptors: their actions and functional roles in health and disease

S Nilsson, JÅ Gustafsson - Nuclear receptors: Current concepts and future …, 2010 - Springer
Our view of estrogen signalling has undergone a paradigm shift over the recent 10–15 years
with the discovery of a second estrogen receptor, ERβ, in 1995 and the finding that …

Estrogen receptor alpha and beta in health and disease

M Jia, K Dahlman-Wright, JÅ Gustafsson - Best practice & research Clinical …, 2015 - Elsevier
Estrogen receptors alpha (ERα) and beta (ERβ) are transcription factors that are involved in
the regulation of many complex physiological processes in humans. Abnormal ER signaling …

Estrogen receptor (ER)-β isoforms: a key to understanding ER-β signaling

YK Leung, P Mak, S Hassan… - Proceedings of the …, 2006 - National Acad Sciences
Estrogen receptor beta (ER-β) regulates diverse physiological functions in the human body.
Current studies are confined to ER-β1, and the functional roles of isoforms 2, 4, and 5 …

Challenging estrogen receptor β with phosphorylation

M Sanchez, N Picard, K Sauvé, A Tremblay - Trends in Endocrinology & …, 2010 - cell.com
From classical gland-based endocrinology to nuclear hormone receptor biology,
tremendous progress has been made in our understanding of hormone responses …

Estrogen receptors (ERα versus ERβ): friends or foes in human biology?

SL Planey, R Kumar, JA Arnott - Journal of Receptors and Signal …, 2014 - Taylor & Francis
Most of the biological effects of estrogens are mediated via the estrogen receptors (ERs) at
the level of gene regulation. Recently, new information regarding the role of ERs in …

[PDF][PDF] Loss of ERβ expression as a common step in estrogen-dependent tumor progression

A Bardin, N Boulle, G Lazennec… - Endocrine-related …, 2004 - erc.bioscientifica.com
The characterization of estrogen receptor beta (ERβ) brought new insight into the
mechanisms underlying estrogen signaling. Estrogen induction of cell proliferation is a …

[HTML][HTML] Update on estrogen signaling

Z Weihua, S Andersson, G Cheng, ER Simpson… - FEBS letters, 2003 - Elsevier
Our understanding of estrogen signaling has undergone a true paradigm shift over recent
years, following the discovery in 1995 of a second estrogen receptor, estrogen receptor β …