Inhibition of tumor progression by naturally occurring terpenoids

G Kuttan, P Pratheeshkumar, KA Manu… - Pharmaceutical …, 2011 - Taylor & Francis
Context: Cancer is a major public health problem in India and many other parts of the world.
Its two main characteristics are uncontrolled cell growth and metastasis. Natural products …

Highlights of pentacyclic triterpenoids in the cancer settings

JAR Salvador, AS Leal, DPS Alho… - Studies in Natural …, 2014 - Elsevier
Pentacyclic triterpenoids comprise a largest class of natural products, bearing several
biological activities, among them anticancer activity. This chapter strolls through the …

Status and challenges of plant-anticancer compounds in cancer treatment

P Garcia-Oliveira, P Otero, AG Pereira, F Chamorro… - Pharmaceuticals, 2021 - mdpi.com
Nowadays, cancer is one of the deadliest diseases in the world, which has been estimated
to cause 9.9 million deaths in 2020. Conventional treatments for cancer commonly involve …

Review on anti-tumor effect of triterpene acid compounds

W Zhang, X Men, P Lei - Journal of cancer research and …, 2014 - journals.lww.com
Recent studies have found that triterpene acid type compounds has many effects including
antiinflammatory, regulating blood sugar level, antiviral and antitumor activity. More …

Targeting cancer with sesterterpenoids: the new potential antitumor drugs

C Zhang, Y Liu - Journal of natural medicines, 2015 - Springer
Cancer remains a major cause of death in the world to date. A variety of anticancer drugs
have been used in clinical chemotherapy, acting on the particular oncogenic abnormalities …

Sesterterpenoids with anticancer activity

A Evidente, A Kornienko, F Lefranc… - Current medicinal …, 2015 - ingentaconnect.com
Terpenes have received a great deal of attention in the scientific literature due to complex,
synthetically challenging structures and diverse biological activities associated with this …

Oleanane-, ursane-, and quinone methide friedelane-type triterpenoid derivatives: Recent advances in cancer treatment

JAR Salvador, AS Leal, AS Valdeira… - European Journal of …, 2017 - Elsevier
Natural pentacyclic triterpenoids (PTs) have been often reported to exhibit a wide range of
biological activities. Among them, the anticancer and anti-inflammatory activities are the …

The role of natural products from plants in the development of anticancer agents

D Twilley, N Lall - Natural Products and Drug Discovery, 2018 - Elsevier
Cancer is one of the major causes of mortality worldwide. In 2012, cancer claimed an
estimated 8.2 million lives, while another 5.8 million people were still living with cancer …

Triterpenoids as new promising anticancer drugs

A Petronelli, G Pannitteri, U Testa - Anti-cancer drugs, 2009 - journals.lww.com
Triterpenoids are structurally diverse organic compounds, characterized by a basic
backbone modified in multiple ways, allowing the formation of more than 20 000 naturally …

Discovery of plant-derived anti-tumor natural products: Potential leads for anti-tumor drug discovery

Z Hui, H Wen, J Zhu, H Deng, X Jiang, XY Ye… - Bioorganic …, 2023 - Elsevier
Natural products represent a paramount source of novel drugs. Numerous plant-derived
natural products have demonstrated potent anti-tumor properties, thereby garnering …