The present study examined to what extent an acute bout of hypotension influences blood
flow in the external carotid artery (ECA) and the corresponding implications for blood flow …

New Findings• What is the central question of this study? Does hypoxia enhance blood flow
to all parts of the brain uniformly?• What is the main finding and its importance? During …

New Findings What is the central question of this study? Dynamic cerebral autoregulation
(CA) is impaired by sympathetic blockade, and the external carotid artery (ECA) vascular …

Cerebral arterioles have been regarded as the primary sites of autoregulatory responses,
whereas the role of large arteries in the cerebral autoregulation is poorly understood. The …

Autoregulation of cerebral blood flow in the face of changing perfusion pressure has been
studied extensively; however, the precise degree to which flow in the microcirculation is …

Key points• The partial pressures of arterial carbon dioxide () and oxygen () has a marked
influence on brain blood flow.• It is unclear if the larger brain arteries are also sensitive to …

Internal carotid artery blood flow (IFBF) was determined in each of nine Macaca mulatta by
means of a flow transducer implanted around an internal carotid artery. The monkeys were …

Reliable assessment of cerebrovascular effectiveness in buffering against pressure
fluctuations may have important implications for the timing and the outcome of therapy after …

We examined 1) whether global cerebral blood flow (CBF) would increase across a 6-h bout
of normobaric poikilocapnic hypoxia and be mediated by a larger increase in blood flow in …

We examined the impact of progressive hypotension with and without hypocapnia on
regional extracranial cerebral blood flow (CBF) and intracranial velocities. Participants …