Materials and Methods Macacus monkeys weighing from 3 to 6 kg. were used. Animals were
subdivided into two groups, acute and chronic. Each animal was anesthetized with …

Herein, we review mechanisms regulating cerebral blood flow (CBF), with specific focus on
humans. We revisit important concepts from the older literature and describe the interaction …

Background and Purpose—To determine how cerebral blood flow (CBF), total and
microvascular cerebral blood volume (CBV), and blood oxygenation level–dependent …

2003). This relationship between CBF and PaCO2, termed cerebral vasomotor reactivity,
provides a measure of cerebral vascular function. Reduction of cerebral vasomotor reactivity …

Understanding the contribution of the autonomic nervous system to cerebral blood flow
(CBF) control is challenging, and interpretations are unclear. The identification of calcium …

We studied whether a hydrostatic pressure gradient between arterial blood and brain tissue
plays a role in the formation of early ischemic cerebral edema after middle cerebral artery …

In isolated rabbit common carotid, internal carotid, and basilar arteries denuded of
endothelium, mounted for measurement of contractile activity, and contracted with 10 …

Cyclic intermittent hypoxia (IH) increases cerebral blood velocity. This enhanced velocity
augments the commensurate shear stimulus and may subsequently increase …

Publisher Summary Cortical pallor, either focal or generalized, was the earliest definite sign
of cortical ischemia. Once pallor was established, spontaneous recolorization of the cortex …

We examined the relationship between cerebral blood flow (CBF) and pial vessel caliber
responses to graded hemorrhagic hypotension at both normocapnia and hypercapnia in 31 …