Near-infrared fluorescence molecular endoscopy detects dysplastic oesophageal lesions using topical and systemic tracer of vascular endothelial growth factor A

WB Nagengast, E Hartmans, PB Garcia-Allende… - Gut, 2019 - gut.bmj.com
The incidence of oesophageal adenocarcinoma (EAC) is steeply rising. Early lesion
detection is a critical factor for improving disease prognosis. We developed and investigated …

[HTML][HTML] Optical imaging with a cathepsin B activated probe for the enhanced detection of esophageal adenocarcinoma by dual channel fluorescent upper GI …

P Habibollahi, JL Figueiredo, P Heidari, AM Dulak… - Theranostics, 2012 - ncbi.nlm.nih.gov
Despite significant advances in diagnosis and treatment, the prognosis of esophageal
adenocarcinoma remains poor highlighting the importance of early detection. Although …

Multimodal endoscope can quantify wide-field fluorescence detection of Barrett's neoplasia

BP Joshi, X Duan, RS Kwon, C Piraka… - …, 2016 - thieme-connect.com
Background and study aims: To demonstrate the clinical use of a multimodal endoscope
with a targeted fluorescently labeled peptide for quantitative detection of Barrett's neoplasia …

Molecular endoscopy for targeted imaging in the digestive tract

JH Lee, TD Wang - The Lancet Gastroenterology & Hepatology, 2016 - thelancet.com
Endoscopy uses optical imaging methods to investigate tissue in a non-destructive manner
with high resolution over a broad range of wavelengths, thus providing a powerful tool to …

Emerging optical methods for surveillance of Barrett's oesophagus

MB Sturm, TD Wang - Gut, 2015 - gut.bmj.com
The rapid rise in incidence of oesophageal adenocarcinoma has motivated the need for
improved methods for surveillance of Barrett's oesophagus. Early neoplasia is flat in …

Endoscopic video-autofluorescence imaging followed by narrow band imaging for detecting early neoplasia in Barrett's esophagus

MA Kara, FP Peters, P Fockens, FJW ten Kate… - Gastrointestinal …, 2006 - Elsevier
BACKGROUND: Video-autofluorescence imaging (AFI) and narrow band imaging (NBI) are
new endoscopic techniques that may improve the detection of high-grade intraepithelial …

Novel imaging modalities in the detection of oesophageal neoplasia

WL Curvers, R Kiesslich, J Bergman - Best practice & research Clinical …, 2008 - Elsevier
The prognosis of oesophageal neoplasia is dependent on the stage of the disease at the
time of detection. Early lesions have an excellent prognosis in contrast to more advanced …

Endoscopic tri-modal imaging for detection of early neoplasia in Barrett's oesophagus: a multi-centre feasibility study using high-resolution endoscopy …

WL Curvers, R Singh, LMWK Song, HC Wolfsen… - Gut, 2008 - gut.bmj.com
Objective: To investigate the diagnostic potential of endoscopic tri-modal imaging and the
relative contribution of each imaging modality (ie high-resolution endoscopy (HRE) …

A protease-activated, near-infrared fluorescent probe for early endoscopic detection of premalignant gastrointestinal lesions

JJ Yim, S Harmsen, K Flisikowski… - Proceedings of the …, 2021 - National Acad Sciences
Fluorescence imaging is currently being actively developed for surgical guidance; however,
it remains underutilized for diagnostic and endoscopic surveillance of incipient colorectal …

Multiplexed endoscopic imaging of Barrett's neoplasia using targeted fluorescent heptapeptides in a phase 1 proof-of-concept study

J Chen, Y Jiang, TS Chang, B Joshi, J Zhou… - Gut, 2021 - gut.bmj.com
Background Oesophageal adenocarcinoma (EAC) is a deadly disease that has increased
dramatically in incidence over the past several decades. 1 2 Endoscopic screening with …