Osteoarthritis (OA) and other degenerative joint diseases are characterized by articular
cartilage destruction, synovial inflammation, sclerosis of subchondral bone, and loss of …

Clinical and animal studies have demonstrated efficacy of mesenchymal stem/stromal cells
(MSCs) in cartilage repair. Although MSCs were originally predicated to mediate tissue …

Osteoarthritis (OA) is one of the most common musculoskeletal diseases, caused by cellular
inflammatory responses and subsequent structural disruption in osteochondral extracellular …

Osteoarthritis (OA) is a degenerative disease of cartilage and bones, which results in
severely compromised quality of life in the aged population. However, currently, no ideal …

Extracellular vesicles (EVs), mainly exosomes and microvesicles, are bilayer lipids
containing biologically active information, including nucleic acids and proteins. They are …

Knee osteoarthritis is the leading cause of functional disability in adults. The goals of knee
osteoarthritis management are directed toward symptomatic pain relief along with the …

Mesenchymal stem cell-derived exosomes (MSC-Exos) have been utilized as medicinal
agents or as delivery vehicles in cartilage injuries and cartilage-based diseases. Given the …

Osteoarthritis (OA) is the most common painful disease with chronic articular cartilage
degeneration. The pathological process of OA is complex and characterized by the …

Osteoarthritis (OA) is a chronic cartilage degeneration disease affecting total joint and with a
wide global impact. Stem cell therapy has emerged as a potential stock for the treatment of …

Osteoarthritis (OA) is a prevalent whole joint disease characterised by cartilage degradation,
subchondral bone sclerosis and bone remodelling, and synovium inflammation, leading to …