Wall teichoic acid (WTA) and lipoteichoic acid (LTA) are structural components of Gram-
positive bacteria's peptidoglycan and cell membrane, which are mostly anionic …

Methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus
faecalis (VRE) have been deemed as serious threats by the CDC. Many chronic MRSA and …

Wall teichoic acids (WTAs) are charged glycopolymers containing phosphodiester-linked
polyol units and represent one of the major components of Gram-positive cell envelope …

Highlights•Teichoic acids are conserved glycopolymers found in Gram-positive cell
envelopes.•LTA biosynthetic genes are essential and good targets for traditional …

A biofilm is an aggregate of microorganisms in which cells adhere to biological or non-
biological surfaces and is responsible for various infectious diseases. Infections caused by …

The peptidoglycan layers of many gram-positive bacteria are densely functionalized with
anionic glycopolymers known as wall teichoic acids (WTAs). These polymers play crucial …

Teichoic acids (TAs) are important for growth, biofilm formation, adhesion and virulence of
Gram-positive bacterial pathogens. The chemical structures of the TAs vary between …

The emergence of bacterial resistance to therapeutic antibiotics limits options for treatment
of common microbial diseases. Subinhibitory antibiotics dosing, often aid in the emergence …

Enterococcus faecalis is among the predominant causes of nosocomial infections. Surface
molecules like d-alanine lipoteichoic acid (LTA) perform several functions in gram-positive …

Staphylococci and most other Gram-positive bacteria incorporate complex teichoic acid (TA)
polymers into their cell envelopes. Several crucial roles in Staphylococcus aureus fitness …