A review of gene-by-air pollution interactions for cardiovascular disease, risk factors, and biomarkers
CK Ward-Caviness - Human genetics, 2019 - Springer
Air pollution is recognized as causal factor for cardiovascular disease (CVD) and is
associated with multiple CVD risk factors. Substantial research effort has been invested in …
associated with multiple CVD risk factors. Substantial research effort has been invested in …
Gene–Air pollution interaction and cardiovascular disease: a review
Genetic susceptibility is likely to play a role in response to air pollution. Hence, gene-
environment interaction studies can be a tool for exploring the mechanisms and the …
environment interaction studies can be a tool for exploring the mechanisms and the …
Association of air pollution exposure and increased coronary artery disease risk: the modifying effect of genetic susceptibility
Z Fu, Y Ma, C Yang, Q Liu, J Liang, Z Weng, W Li… - Environmental …, 2023 - Springer
Background Both genetic factors and air pollution are risk factors for coronary artery disease
(CAD), but their combined effects on CAD are uncertain. The study aimed to …
(CAD), but their combined effects on CAD are uncertain. The study aimed to …
[HTML][HTML] Genome-wide gene-air pollution interaction analysis of lung function in 300,000 individuals
CA Melbourne, AM Erzurumluoglu, N Shrine… - Environment …, 2022 - Elsevier
Background Impaired lung function is predictive of mortality and is a key component of
chronic obstructive pulmonary disease. Lung function has a strong genetic component but is …
chronic obstructive pulmonary disease. Lung function has a strong genetic component but is …
Leveraging the comparative toxicogenomics database to fill in knowledge gaps for environmental health: a test case for air pollution-induced cardiovascular disease
AP Davis, TC Wiegers, CJ Grondin… - Toxicological …, 2020 - academic.oup.com
Environmental health studies relate how exposures (eg, chemicals) affect human health and
disease; however, in most cases, the molecular and biological mechanisms connecting an …
disease; however, in most cases, the molecular and biological mechanisms connecting an …
From air pollution to cardiovascular diseases: the emerging role of epigenetics
The association between air pollution and a wide-ranging spectrum of acute and chronic
disorders—including cardiovascular diseases—is widely acknowledged. Exposure to …
disorders—including cardiovascular diseases—is widely acknowledged. Exposure to …
Potential biological mediators of myocardial and vascular complications of air pollution—a state-of-the-art review
Ambient air pollution is recognised globally as a significant contributor to the burden of
cardiovascular diseases. The evidence from both human and animal studies supporting the …
cardiovascular diseases. The evidence from both human and animal studies supporting the …
Consequences of exposure to pollutants on respiratory health: From genetic correlations to causal relationships
Modern society grew rapidly over the last few decades and this led to an alarming increase
in air pollutants and a worsening of the human health, especially in relation to the respiratory …
in air pollutants and a worsening of the human health, especially in relation to the respiratory …
Gene-by-environment interactions in urban populations modulate risk phenotypes
Uncovering the interaction between genomes and the environment is a principal challenge
of modern genomics and preventive medicine. While theoretical models are well defined …
of modern genomics and preventive medicine. While theoretical models are well defined …
[HTML][HTML] Candidate gene expression in response to low-level air pollution
Background Epidemiological studies have linked air pollutant to adverse health effects even
at low exposure levels, but limited evidence is available on its associations with gene …
at low exposure levels, but limited evidence is available on its associations with gene …
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