Introduction: FRI is a validated computational fluid dynamics (CFD)-based technique using
aerosol delivery performance profile, patients' high-resolution lung CT scans and patient …

Background: Functional respiratory imaging (FRI) is a computational fluid dynamics-based
technique using three-dimensional models of human lungs and formulation profiles to …

Chronic obstructive pulmonary disease (COPD) is a progressive inflammatory condition of
the airways, pulmonary vessels, and lung parenchyma, distinguished by airflow limitation …

Introduction: Drugs used in asthma or COPD exacerbation are delivered to the lungs by
inhalation. This is facilitated, among other factors, by the use of dry powder inhalers (DPIs) …

One of the top three causes of death worldwide is due to chronic obstructive pulmonary
disease (COPD)(1). According to the World Health Association (WHO) in 2019, there were 7 …

Considering the magnitude of chronic obstructive pulmonary disease (COPD) and its impact
on the world population, the advances in the understanding and treatment of this disease …

Background: Inhalation therapy is a cornerstone of treating patients with chronic obstructive
pulmonary disease (COPD). Inhaler types and through-device inhalation parameters …

INTRODUCTION Inhaled drugs can only be effective if they reach the middle and small
airways. This study introduces a system that combines a trans-nasal application of aerosols …

Introduction: FRI is a novel computational fluid dynamics (CFD)-based technique using
formulation profile and patients lung CT scan to simulate aerosol deposition. Aims and …