New developments in inhaled drugs: within and beyond the lungs
OS Usmani - Respiration, 2014 - karger.com
Inhalation medicine and aerosol science are 'Cinderella'disciplines, where the
breakthroughs and advances in formulation science, biopharmaceutics, device engineering …
breakthroughs and advances in formulation science, biopharmaceutics, device engineering …
Airway epithelial cell function and respiratory host defense in chronic obstructive pulmonary disease
GD Amatngalim, PS Hiemstra - Chinese medical journal, 2018 - journals.lww.com
Our lungs have a vital role in mediating the exchange of oxygen and carbon dioxide
between the air we breathe and the body. This function is under constant pressure as …
between the air we breathe and the body. This function is under constant pressure as …
Assessing drug deposition efficacies, environmental impact and affordability for inhalers among chronic respiratory diseases: A systematic review
RN Wasnik, M Cope, A Cowan, S Pakhale - medRxiv, 2024 - medrxiv.org
Introduction Chronic respiratory diseases such as asthma, COPD, and other pulmonary
conditions impose a substantial global health burden, affecting millions of individuals …
conditions impose a substantial global health burden, affecting millions of individuals …
COPD: Moving Beyond Physiological Reductionism.
EFM Wouters - COPD: Journal of Chronic Obstructive Pulmonary …, 2011 - Taylor & Francis
Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality
throughout the world: it is the fourth leading cause of death in the world and further …
throughout the world: it is the fourth leading cause of death in the world and further …
Exhaled nitric oxide in COPD: glancing through a smoke screen
PJ Sterk, H De Gouw, FLM Ricciardolo, KF Rabe - Thorax, 1999 - thorax.bmj.com
There is worldwide increasing awareness of the human and socioeconomic impact of
chronic obstructive pulmonary disease (COPD) which is a major cause of morbidity and …
chronic obstructive pulmonary disease (COPD) which is a major cause of morbidity and …
The air we breathe: respiratory impact of indoor air quality in chronic obstructive pulmonary disease
T Mkorombindo, JR Balmes, A Custovic… - American Journal of …, 2022 - atsjournals.org
The global push for clean air has garnered much attention because of the deleterious health
and environmental effects of poor air quality (1). Presently, more than 90% of the worldes …
and environmental effects of poor air quality (1). Presently, more than 90% of the worldes …
Cytokines as targets in chronic obstructive pulmonary disease
KF Chung - Current drug targets, 2006 - ingentaconnect.com
Chronic obstructive pulmonary disease [COPD] is characterised by airflow limitation of
peripheral airways that is not fully reversible and progressive and is associated with an …
peripheral airways that is not fully reversible and progressive and is associated with an …
Extent of inhaled drug deposition in mouth-throat and pulmonary airways: a novel biophysical modelling approach for inhaled therapeutics
A Kuttler, T Dimke - 2015 - Eur Respiratory Soc
Introduction: To quantitatively investigate sources of inter-& intra-individual variability of
inhaled delivery of drugs to the lungs, we describe here a novel modelling and simulation …
inhaled delivery of drugs to the lungs, we describe here a novel modelling and simulation …
Targeted Lung Deposition From Nebulization Is Not Improved in the Lateral Decubitus Position in Healthy Volunteers
G Reychler, M San Miguel-Pagola, AS Aubriot… - Respiratory …, 2019 - rc.rcjournal.com
BACKGROUND: Clinical benefits of inhaled therapies are related to the amount of drug
deposited in the targeted area of the lung. Body positions that influence the distribution of …
deposited in the targeted area of the lung. Body positions that influence the distribution of …
Inhaler devices for patients with COPD
JB Fink, GL Colice, R Hodder - COPD: Journal of Chronic …, 2013 - Taylor & Francis
Chronic obstructive pulmonary disease (COPD) continues to be associated with increased
morbidity and mortality risk in spite of updated guidelines and a better understanding of this …
morbidity and mortality risk in spite of updated guidelines and a better understanding of this …