Although the cause of multiple sclerosis (MS) has remained obscure, many findings support
an autoimmune pathogenesis on the background of a complex interaction between multiple …

Multiple sclerosis (MS), an incurable but manageable disorder, is characterized by chronic
inflammatory demyelination and neurodegeneration in the central nervous system. Although …

Several of the emerging therapies focusing on immune-mediated disease mechanisms
seem to offer stronger efficacy than the currently approved immune modulators for MS …

We have entered a golden era in multiple sclerosis (MS) research. Two decades ago, our
understanding of the disease was largely descriptive and there were no approved therapies …

Although several therapies exist for multiple sclerosis (MS), the most common inflammatory
demyelinating disease of the central nervous system (CNS), there remains a large unmet …

New insights into the complex immunopathogenesis of multiple sclerosis have led to a
proliferation of promising new therapeutic strategies. While the current armamentarium of …

Multiple sclerosis (MS) is a neurological disorder of the central nervous system with a
presentation and disease course that is largely unpredictable. MS can cause loss of …

Multiple sclerosis is a chronic inflammatory demyelinating disease of the central nervous
system. Both genetic and environmental factors are believed to contribute to the …

Multiple sclerosis (MS) is an autoimmune disease triggered by environmental factors that act
on a genetically susceptible host. It features three clinical stages: a pre-clinical stage …

Recent years have seen considerable evolution and increasing sophistication of our
concepts of the pathophysiology of multiple sclerosis. These new notions include the …