[HTML][HTML] Freeze-drying: an alternative method for the analysis of volatile organic compounds in the headspace of urine samples using solid phase micro-extraction …

RBM Aggio, A Mayor, S Coyle, S Reade… - Chemistry Central …, 2016 - Springer
Abstract Background Volatile organic compounds (VOCs) can be intermediates of metabolic
pathways and their levels in biological samples may provide a better understanding about …

Simultaneous determination of volatile organic compounds with a wide range of polarities in urine by headspace solid‐phase microextraction coupled to gas …

HN Song, CH Kim, WY Lee… - Rapid Communications in …, 2017 - Wiley Online Library
Rationale Volatile organic compounds (VOCs) are ubiquitous environmental pollutants that
have a high vapor pressure at room temperature. Some VOCs have been classified as …

Headspace solid-phase microextraction coupled with gas chromatography–mass spectrometry for the determination of volatile organic compounds in urine

N Drabińska, M Starowicz, U Krupa-Kozak - Journal of Analytical …, 2020 - Springer
Determination of volatile organic compounds (VOCs), the metabolites produced in human
body, contributes to better understanding of the mechanisms responsible for the progression …

Headspace SPME-GC-MS metabolomics analysis of urinary volatile organic compounds (VOCs)

S Zhang, D Raftery - Mass Spectrometry in Metabolomics: Methods and …, 2014 - Springer
In this chapter, we describe the procedure for metabolic profiling of hundreds of urinary
volatile organic compounds (VOCs) using headspace solid-phase microextraction (SPME) …

[HTML][HTML] Optimisation of urine sample preparation for headspace-solid phase microextraction gas chromatography-mass spectrometry: altering sample pH, sulphuric …

P Aggarwal, J Baker, MT Boyd, S Coyle, C Probert… - Metabolites, 2020 - mdpi.com
Headspace-solid phase microextraction gas chromatography-mass spectrometry (HS-SPME-
GC-MS) can be used to measure volatile organic compounds (VOCs) in human urine …

Headspace solid-phase microextraction profiling of volatile compounds in urine: application to metabolic investigations

GA Mills, V Walker - Journal of Chromatography B: Biomedical Sciences …, 2001 - Elsevier
Volatile compounds contribute substantially to the metabolic pool in man. Their analysis in
body fluids is problematic. We investigated headspace solid-phase microextraction (HS …

[PDF][PDF] Optimisation of sample preparation for direct SPME-GC-MS analysis of murine and human faecal volatile organic compounds for metabolomic studies

S Reade, A Mayor, R Aggio, T Khalid… - J Anal Bioanal …, 2014 - researchgate.net
The analysis of volatile organic compounds (VOCs) emitted from biological fluids such as
blood, urine, breath and faeces, has been receiving more attention from researchers and …

[HTML][HTML] An optimization of liquid–liquid extraction of urinary volatile and semi-volatile compounds and its application for gas chromatography-mass spectrometry and …

N Drabińska, P Młynarz, B de Lacy Costello, P Jones… - Molecules, 2020 - mdpi.com
Urinary volatile compounds (VCs) have been recently assessed for disease diagnoses.
They belong to very diverse chemical classes, and they are characterized by different …

Optimisation and validation of a HS-SPME–GC–IT/MS method for analysis of carbonyl volatile compounds as biomarkers in human urine: Application in a pilot study to …

I Calejo, N Moreira, AM Araújo, M Carvalho… - Talanta, 2016 - Elsevier
A new and simple analytical approach consisting of an automated headspace solid-phase
microextraction (HS-SPME) sampler coupled to gas chromatography-ion trap/mass …

Gas chromatographic-mass spectrometric analysis of urinary volatile organic metabolites: Optimization of the HS-SPME procedure and sample storage conditions

TŽ Semren, IB Karačonji, T Safner, N Brajenović… - Talanta, 2018 - Elsevier
Non-targeted metabolomics research of human volatile urinary metabolome can be used to
identify potential biomarkers associated with the changes in metabolism related to various …