Background. Family history of prostate cancer is a risk factor for prostate cancer occurrence.
Differently from other neoplasms no major predisposing gene has been identified. Material …

BACKGROUND The definition of hereditary prostate cancer (HPC) is based on family history
and age at onset. Intuitively, HPC is a serious subtype of prostate cancer but there are only …

Background The purpose of the study was to determine the relationship between family
history of prostate cancer in a first-degree relative (FDR) and prostate cancer incidence and …

OBJECTIVES: To study attitudes regarding possible inheritance of prostate cancer among
sons of men with prostate cancer. METHODS: A questionnaire was sent to 69 men with …

Abstract Introduction: The African-American Hereditary Prostate Cancer (AAHPC) Study was
designed to recruit African-American families fulfilling very stringent criteria of four or more …

BACKGROUND Familial associations between cancer sites may implicate true familial
clustering which is relevant for the identification of new cancer syndromes and for clinical …

Objectives. To confirm, in a study of a large, independent cohort of families with prostate
cancer, the findings of three segregation analyses that have suggested the existence of an …

Objective To assess the value of a positive family history (FH) as a risk factor for prostate
cancer incidence and grade among men undergoing organised prostate‐specific antigen …

OBJECTIVES: To compare the clinical and biologic features at diagnosis between sporadic
and familial clinically localized prostate cancer (CaP), and to compare the prognosis of …

Background: Familial prostate cancer risk estimates are inflated by clinically insignificant low-
risk cancer, diagnosed after prostate-specific antigen testing. We provide age-specific …