BACKGROUND. The identification and treatment of individuals with tuberculosis (TB) is a
global public health priority. Accurate diagnosis of pulmonary active TB (ATB) disease …

Background Diagnosis of active tuberculosis (ATB) currently relies on detection of
Mycobacterium tuberculosis (Mtb). Identifying patients with extrapulmonary TB (EPTB) …

Background Early and accurate diagnosis followed by timely treatment are the key
prerequisites to fight tuberculosis (TB) and reduce its global burden. Despite scientific …

Background: The analysis of phenotypic characteristics on Mycobacterium tuberculosis
(MTB)-specific T cells is a promising approach for the diagnosis of active tuberculosis (aTB) …

Diagnosis of pulmonary tuberculosis (TB) disease, the most common cause of death due to
infection globally [1], depends on direct detection of Mycobacterium tuberculosis, typically …

Objectives To identify new potential host biomarkers in blood to discriminate between active
TB patients, uninfected (NoTBI) and latently infected contacts (LTBI). Methods A blood cell …

Objective We aimed to determine whether combinations of multiplex cytokine responses
could differentiate Mycobacterium tuberculosis (Mtb) infection states. Methods Mtb-specific …

Objectives The development of non‐sputum‐based assays for tuberculosis (TB) diagnosis
and treatment monitoring is a key priority. Recent data indicate that whole blood‐based …

Tuberculosis (TB) treatment monitoring is paramount to clinical decision-making and the
host biomarkers appears to play a significant role. The currently available diagnostic …

Background. Changes in the phenotype and function of Mycobacterium tuberculosis (M.
tuberculosis)-specific CD4+ and CD8+ T-cell subsets in response to stage of infection may …