Quercetin's Effects on Intestinal Polyp Multiplicity and Macrophage Number in the Apc Min/+ Mouse

EA Murphy, JM Davis, JL McClellan… - Nutrition and …, 2011 - Taylor & Francis
Numerous in vitro studies argue for quercetin's chemopreventive potential in colon cancer;
however, experimental studies in rodents are limited. Macrophages play a role in …

Quercetin suppresses early colon carcinogenesis partly through inhibition of inflammatory mediators

ND Turner, KJ Paulhill, CA Warren… - … Symposium on Human …, 2007 - actahort.org
We have demonstrated that 0.45% quercetin added to a diet containing corn oil (15% w/w),
as the lipid source, and cellulose (6% w/w), as the fiber source, was able to suppress the …

Dietary quercetin, immune functions and colonic carcinogenesis in rats

JH Exon, BA Magnuson, EH South… - Immunopharmacology …, 1998 - Taylor & Francis
Rats fed 100 mg/kg quercetin (QUE) daily for 7 weeks had significantly enhanced natural
killer cell activity compared to their vehicle (VEH)-fed control. In contrast, rats fed 100 mg/kg …

[HTML][HTML] Quercetin may suppress rat aberrant crypt foci formation by suppressing inflammatory mediators that influence proliferation and apoptosis

CA Warren, KJ Paulhill, LA Davidson, JR Lupton… - The Journal of …, 2009 - Elsevier
The flavonoid quercetin suppresses cell proliferation and enhances apoptosis in vitro. In this
study, we determined whether quercetin protects against colon cancer by regulating the …

Suppression of intestinal crypt cell proliferation and aberrant crypt foci by dietary quercetin in rats

JM Gee, H Hara, IT Johnson - Nutrition and cancer, 2002 - Taylor & Francis
Quercetin inhibits proliferation of human gastric and colonic cancer cells in vitro by
suppressing mitosis and increasing apoptosis. Quercetin might therefore act as an …

[HTML][HTML] Quercetin, but not its glycosidated conjugate rutin, inhibits azoxymethane-induced colorectal carcinogenesis in F344 rats

AA Dihal, VCJ de Boer, H van der Woude… - The Journal of …, 2006 - Elsevier
The effect of the flavonoid quercetin and its conjugate rutin was investigated on (biomarkers
of) colorectal cancer (CRC). Male F344 rats (n= 42/group) were fed 0, 0.1, 1, or 10 g …

Association of dietary quercetin with reduced risk of proximal colon cancer

Z Djuric, RK Severson, I Kato - Nutrition and cancer, 2012 - Taylor & Francis
Quercetin is a flavonol that appears to be protective against several cancers, but its possible
role in prevention of colorectal cancer is not yet well studied. We evaluated dietary intakes of …

Dietary quercetin and rutin: Inhibitors of experimental colonic neoplasia

EE Deschner - 1992 - ACS Publications
The phenolic flavonoids quercetin (QU) and rutin (RU) found in the outer leaves of
vegetables and fruits were examined as modifiers of an experimental model of colon cancer …

Plant phenolics decrease intestinal tumors in an animal model of familial adenomatous polyposis

NN Mahmoud, AM Carothers, D Grunberger… - …, 2000 - academic.oup.com
Epidemiological studies consistently indicate that consumption of fruits and vegetables
lowers cancer risk in humans and suggest that certain dietary constituents may be effective …

Chemoprevention studies of the flavonoids quercetin and rutin in normal and azoxymethane-treated mouse colon

K Yang, SA Lamprecht, Y Liu, H Shinozaki… - …, 2000 - academic.oup.com
In this study we investigated the chemopreventive effects of quercetin and rutin when added
to standard AIN-76A diet and fed to normal and azoxymethane (AOM)-treated mice. Early …