Purpose Sjögren syndrome (SS) secondary to rheumatoid arthritis (RA) affects lacrimal and
salivary glands, and therefore dry eye syndrome (DES) is more prevalent in patients with …

Dry eye disease (DED) is a challenge in ophthalmology. Rat models represent valuable
tools to study the pathophysiology and to develop novel treatments. A major challenge in …

Purpose: Biomarkers with minimally invasive and reproducible objective metrics provide the
key to future paradigm shifts in understanding of the underlying causes of dry eye disease …

Introduction: Changes in tear protein concentrations may reflect ocular surface health. This
study analyzes changes in tear protein concentrations of young Malays with dry eye (DE) …

Dry eye disease (DED) represents a heterogeneous group of conditions with tear film
insufficiency and signs and/or symptoms of ocular surface irritation. The clinical …

Dry eye disease (DED) is a commonly encountered ophthalmic condition that is recognized
to have significant effects on visual function, work productivity, and quality of life. 1 In recent …

Purpose This study compares signs, symptoms and predictive tools used to diagnose dry
eye disease (DED) and ocular surface disorders in six systemic well-defined and non …

Purpose: To assess whether tear hyperosmolarity, being diagnostic of dry eye disease
(DED), is associated with specific alterations to the cytokine content of human tears that may …

Purpose.: The purpose of this study was to determine whether aqueous-deficient dry eyes
(ADDE) is a protein conformational disease. Up to now the therapeutic regimen has been …

The main focus in clinical proteomics is the discovery of new protein or peptide biomarkers
which are correlated with a certain disease. Tear proteins have been investigated …