Dry eye disease (DED) is a heterogenous disease of the ocular surface. Multiple
pathogenetic factors are responsible for the disease process, but DED is generally linked to …

Purpose:: The purpose of this study was to evaluate the relationship between signs and
symptoms of dry eye disease in a general patient population. Methods:: In a retrospective …

The ocular surface refers to the outermost layer of the eye, which includes the cornea,
conjunctiva and eyelids [1]. It is a complex and delicate system that is responsible for …

Dry eye disease (DED) is a multifactorial disease of the ocular surface characterized by
disruption of tear film homeostasis, causing ocular symptoms that include visual disturbance …

Dry eye syndrome (DES) is a growing public health concern with a high global prevalence;
however, the fundamental processes involved in its pathogenic mechanisms remain poorly …

ABSTRACT Introduction Dry Eye Disease (DED) is defined as a multifactorial disease of the
ocular surface characterized by a loss of homeostasis of the tear film, and a vicious cycle of …

Dry eye disease (DED) is a multifactorial disorder that leads to ocular discomfort, visual
disturbance, and tear film instability. DED is accompanied by an increase in tear osmolarity …

The proteins found in tears have an important role in the maintenance of the ocular surface
and changes in the quality and quantity of tear components reflect changes in the health of …

Purpose To characterize the tear film peptidome and low molecular weight protein profiles of
healthy control individuals, and to evaluate changes due to day-to-day and individual …

Validated biomarkers to be used as biological tools for managing ocular surface diseases
(OSDs) are still an unmet need in daily clinical practice. Many studies have contributed to …