Purpose To investigate effects of punctal occlusion on global tear protein levels in patients
with dry eye. Methods In this prospective, longitudinal, single-center study, nonabsorbable …

The definition and diagnostic criteria of dry eye disease (DED) proposed by the Japan Dry
Eye Society and other countries are reviewed. The first definition and criteria of DED in …

Purpose To evaluate how increasing age is associated with dry eye disease (DED) signs
and symptoms in the Dry Eye Assessment and Management (DREAM) study. This study was …

Purpose Some systemic medications are reported to be associated with dry eye disease
(DED), yet their associations with the severity of DED signs and symptoms are not well …

A thin layer of tears covers the ocular surface. The tears are a complex fluid comprised of
secretions from a number of sources including the lacrimal gland, goblet cells, cornea, and …

In the diagnostic process of dry eye disease, the detection of inflammatory activity is critical
in order to evaluate the risk of progression and immunologic shift of the disease, to predict …

Dry eye disease (DED) is one of the most frequent conditions in ophthalmology. The early
diagnosis and the monitoring of therapy efficacy may help to prevent the severe …

Background—It is recognized that inflammation is an underlying cause of dry eye disease
(DED), with cytokine release involved. We systematically reviewed literature with meta …

Purpose.: Diabetesmellitus has been shown to be associated with and complicated by dry
eye syndrome. We sought to examine and compare the tear film proteome of type 2 diabetic …

Purpose To evaluate and compare the efficacy and safety of two investigational artificial tear
formulations (CHO-1 and CHO-2) containing carmellose sodium, hyaluronic acid at different …