Distributive conjugal transfer: new insights into horizontal gene transfer and genetic exchange in mycobacteria

KM Derbyshire, TA Gray - Molecular Genetics of Mycobacteria, 2014 - Wiley Online Library
Eukaryotes use meiotic recombination to blend parental genomes and generate genome‐
wide variation between progeny. By contrast, bacteria divide asexually to generate two …

Blending genomes: distributive conjugal transfer in mycobacteria, a sexier form of HGT

TA Gray, KM Derbyshire - Molecular microbiology, 2018 - Wiley Online Library
This review discusses a novel form of horizontal gene transfer (HGT) found in mycobacteria
called Distributive Conjugal Transfer (DCT). While satisfying the criteria for conjugation, DCT …

Unconventional conjugal DNA transfer in mycobacteria

J Wang, LM Parsons, KM Derbyshire - Nature genetics, 2003 - nature.com
Bacterial conjugation is an active process that results in unidirectional transfer of DNA from a
donor to a recipient cell. Most transfer systems are plasmid-encoded and require proteins to …

First description of natural and experimental conjugation between mycobacteria mediated by a linear plasmid

MCDS Rabello, CK Matsumoto, LGP de Almeida… - PloS one, 2012 - journals.plos.org
Background In a previous study, we detected the presence of a Mycobacterium avium
species-specific insertion sequence, IS 1245, in Mycobacterium kansasii. Both species were …

Distributive conjugal transfer in mycobacteria generates progeny with meiotic-like genome-wide mosaicism, allowing mapping of a mating identity locus

TA Gray, JA Krywy, J Harold, MJ Palumbo… - PLoS …, 2013 - journals.plos.org
Horizontal gene transfer (HGT) in bacteria generates variation and drives evolution, and
conjugation is considered a major contributor as it can mediate transfer of large segments of …

Recent history of trans-kingdom conjugation

GC Ferguson, JA Heinemann - Horizontal Gene Transfer, 2002 - Elsevier
Publisher Summary This chapter discusses the history of trans-kingdom conjugation.
Conjugation is a mechanism of horizontal gene transfer (HGT) first observed among …

Chromosomal DNA transfer in Mycobacterium smegmatis is mechanistically different from classical Hfr chromosomal DNA transfer

J Wang, PK Karnati, CM Takacs… - Molecular …, 2005 - Wiley Online Library
Classical conjugal DNA transfer of chromosomal DNA in bacteria requires the presence of a
cis‐acting site, oriT, in the chromosome. Acquisition of an oriT occurs if a conjugative …

Conjugal transfer of chromosomal DNA in Mycobacterium smegmatis

LM Parsons, CS Jankowski… - Molecular …, 1998 - Wiley Online Library
The genus Mycobacterium includes the major human pathogens Mycobacterium
tuberculosis and Mycobacterium leprae. The development of rational drug treatments for the …

Mechanisms of horizontal gene transfer and DNA recombination

GW Blakely - Molecular medical microbiology, 2024 - Elsevier
Comparative genomics is revealing extensive diversity within many bacterial species. The
pan-genome of a species is composed of core genes present in all strains and dispensable …

Retrotransfer in Escherichia coli conjugation: bidirectional exchange or de novo mating?

JA Heinemann, RG Ankenbauer - Journal of bacteriology, 1993 - Am Soc Microbiol
DNA can be transferred among eubacteria and to plants and fungi by related, plasmid-
mediated processes collectively referred to as bacterial conjugation. Conjugation occurs …