Histone post-translational modifications and CircRNAs in mouse and human spermatozoa: potential epigenetic marks to assess human sperm quality

T Chioccarelli, R Pierantoni, F Manfrevola… - Journal of clinical …, 2020 - mdpi.com
Spermatozoa (SPZ) are motile cells, characterized by a cargo of epigenetic information
including histone post-translational modifications (histone PTMs) and non-coding RNAs …

Expression patterns of circular RNAs in high quality and poor quality human spermatozoa

T Chioccarelli, F Manfrevola, B Ferraro… - Frontiers in …, 2019 - frontiersin.org
Circular RNAs (circRNAs) are expressed in human testis and seminal plasma. Until today,
there is missing information about a possible payload of circRNAs in human spermatozoa …

Identification of circular RNAs in porcine sperm and evaluation of their relation to sperm motility

M Gòdia, A Castelló, M Rocco, B Cabrera… - Scientific reports, 2020 - nature.com
Circular RNAs (circRNAs) are emerging as a novel class of noncoding RNAs which potential
role as gene regulators is quickly gaining interest. circRNAs have been studied in different …

Identification and characterization of human testis derived circular RNAs and their existence in seminal plasma

WW Dong, HM Li, XR Qing, DH Huang, HG Li - Scientific reports, 2016 - nature.com
Circular RNAs (circRNAs) have emerged as novel molecules of interest in gene regulation
as other noncoding RNAs. Though they have been explored in some species and tissues …

CircNAPEPLD is expressed in human and murine spermatozoa and physically interacts with oocyte miRNAs

M Ragusa, D Barbagallo, T Chioccarelli… - RNA biology, 2019 - Taylor & Francis
Circular RNAs (circRNAs) have a critical role in the control of gene expression. Their
function in spermatozoa (SPZ) is unknown to date. Twenty-eight genes, involved in …

A novel protein encoded by circRsrc1 regulates mitochondrial ribosome assembly and translation during spermatogenesis

S Zhang, C Wang, Y Wang, H Zhang, C Xu, Y Cheng… - BMC biology, 2023 - Springer
Abstract Background Circular RNAs (circRNAs) are a large class of mammalian RNAs.
Several protein products translated by circRNAs have been reported to be involved in the …

Novel insights into circRNA saga coming from spermatozoa and epididymis of HFD mice

F Manfrevola, T Chioccarelli, VG Mele… - International Journal of …, 2023 - mdpi.com
Obesity is a pathophysiological disorder associated with adiposity accumulation, oxidative
stress, and chronic inflammation state that is progressively increasing in younger population …

The roles of cirRNA in the development of germ cells

Y Cai, X Lei, Z Chen, Z Mo - Acta Histochemica, 2020 - Elsevier
Circular RNA (CircRNA), a type of endogenous non-coding RNAs (ncRNAs), is generally
generated from precursor mRNA (pre-mRNA) by canonical splicing and head-to-tail back …

Circular RNAs: biogenesis, expression and their potential roles in reproduction

G Quan, J Li - Journal of ovarian research, 2018 - Springer
Unlike other non-coding RNAs (ncRNAs), circular RNA (circRNA) is generally presented as
a covalently linked circle lacking both a 5′ cap and a 3′ tail. circRNAs were thought to be …

The role of circular RNAs in the physiology and pathology of the mammalian ovary

J Zhang, C Wang, C Jia, Y Zhang, X Qing… - International Journal of …, 2022 - mdpi.com
Circular RNAs (circRNAs) are an abundant class of endogenous non-coding RNAs
(ncRNAs) generated from exonic, intronic, or untranslated regions of protein-coding genes …