Adrenal suppression secondary to inhaled fluticasone propionate

AV Taylor, N Laoprasert, D Zimmerman… - Annals of Allergy, Asthma …, 1999 - Elsevier
BACKGROUND: Inhaled glucocorticoids are the medical treatment of choice in many of
patients with asthma. Fluticasone propionate is an inhaled glucocorticoid with little systemic …

Moderate dose inhaled corticosteroid-induced symptomatic adrenal suppression: case report and review of the literature

RH Schwartz, O Neacsu, DP Ascher… - Clinical …, 2012 - journals.sagepub.com
Inhaled corticosteroids (ICS) are drugs of choice for persistent asthma. Less than 500 µg/d of
fluticasone are believed to be safe. We found 92 cases of adrenal suppression in PubMed; …

The effect of a steroid “burst” and long-term, inhaled fluticasone propionate on adrenal reserve

KL Nguyen, D Lauver, I Kim, M Aresery - Annals of Allergy, Asthma & …, 2003 - Elsevier
BACKGROUND: Although widely used, the effects of steroid “bursts” on the hypothalamic-
pituitary-adrenal axis, especially with long-term, concomitant topical steroids use, have not …

Hypothalamic-pituitary-adrenal axis suppression associated with the use of inhaled fluticasone propionate

JE Duplantier, RP Nelson, AR Morelli… - Journal of allergy and …, 1998 - jacionline.org
DISCUSSION Inhaled corticosteroids have previously been reported to cause Cushing
syndrome in rare cases. 1 Inhaled FP is considered to be a safe and effective medication …

Adrenal suppression in two patients with asthma treated with low doses of the inhaled steroid fluticasone propionate

B Zimmerman, M Gold, D Wherrett, AK Hanna - Journal of allergy and …, 1998 - Elsevier
Adrenal suppression in two patients with asthma treated with low doses of the inhaled steroid
fluticasone propionate - ScienceDirect Skip to main contentSkip to article Elsevier logo Journals & …

Adrenal suppression from high-dose inhaled fluticasone propionate in children with asthma

D Sim, A Griffiths, D Armstrong, C Clarke… - European …, 2003 - Eur Respiratory Soc
This cross-sectional study was designed to examine the prevalence of adrenocortical
suppression in children with asthma treated with high-dose inhaled fluticasone propionate …

Acute adrenal insufficiency in a patient with asthma after changing from fluticasone propionate to budesonide

GRG Todd, D Wright, M Ryan - Journal of allergy and clinical …, 1999 - jacionline.org
High-dose inhaled corticosteroids have been associated with basal adrenocortical
suppression, but usually without clinical consequences. 1 Clinically significant adrenal …

Suppression of hypothalamic-pituitary-adrenal axis activity with inhaled flunisolide and fluticasone propionate in adult asthma patients

TB Casale, HS Nelson, WE Stricker, H Raff… - Annals of Allergy …, 2001 - Elsevier
BACKGROUND: Suppression of the hypothalamic-pituitary-adrenal (HPA) axis, a potential
systemic effect of inhaled corticosteroid therapy, can be quantified by monitoring serum …

Fluticasone propionate results in improved glucocorticoid receptor binding affinity and reduced oral glucocorticoid requirements in severe asthma

SR Nimmagadda, JD Spahn, HS Nelson… - Annals of Allergy …, 1998 - Elsevier
BACKGROUND: Inhaled glucocorticoids (iGC) have become important first line agents in the
management of moderate-to-severe asthma. Severe asthma is associated with reduced …

Time to onset of effect of fluticasone propionate in patients with asthma

SJ Szefler, HA Boushey, DS Pearlman, A Togias… - Journal of allergy and …, 1999 - Elsevier
Background: The effectiveness of inhaled glucocorticoids in the treatment of asthma is well
documented; however, times to onset and maximal treatment effects of these agents have …