Use of selective in-vivo tau imaging will enable improved understanding of tau aggregation
in the brain, facilitating research into causes, diagnosis, and treatment of major tauopathies …

In vivo imaging of tau pathology will provide new insights into tau deposition in the human
brain, thus facilitating research into causes, diagnosis and treatment of major dementias …

Background Deposition of tau aggregates is a pathological hallmark of Alzheimer's disease
that is closely linked both spatially and temporally to emergence of neurodegeneration and …

The military conflicts of the last decade have highlighted the growing problem of traumatic
brain injury in combatants returning from the battlefield. The considerable evidence pointing …

The pathway leading from soluble and monomeric to hyperphosphorylated, insoluble and
filamentous tau protein is at the centre of many human neurodegenerative diseases …

Background Plasma tau phosphorylated at threonine 217 (p-tau217) and plasma tau
phosphorylated at threonine 181 (p-tau181) are associated with Alzheimer's disease tau …

Aggregated tau protein is a major neuropathological substrate central to the
pathophysiology of neurodegenerative diseases such as Alzheimer's disease (AD) …

Pathological accumulated misfolded tau underlies various neurodegenerative diseases and
associated clinical syndromes. To diagnose those diseases reliable before death or even at …

Abstract Alzheimer's Association Research Roundtable Fall 2015—Tau: From research to
clinical development. Tau pathology is recognized as the key driver of disease progression …

Tauopathies are a group of over 20 clinicopathological neurodegenerative diseases
including Alzheimer's disease (AD), the most common type of dementia, progressive …