Migraine is a debilitating neurological disorder that affects about 12% of the population. In
the past decade, the role of the neuropeptide calcitonin gene-related peptide (CGRP) in …

The individual and global burden of migraine is of such significance that there are
accelerated efforts to develop new therapies. New migraine therapeutics are needed to …

Recently developed calcitonin gene‐related peptide (CGRP) receptor antagonistic
molecules have shown promising results in clinical trials for acute treatment of migraine …

Migraine is a common neurological disorder that is associated with an increase in plasma
calcitonin gene-related peptide (CGRP) levels. CGRP, a neuropeptide released from …

Background According to the neurovascular theory of migraine, activation of the
trigeminovascular system contributes to the development of migraine. This study examined …

Calcitonin gene-related peptide (CGRP) seems to play a major role in migraine mechanism.
Overwhelming data report the efficacy of small molecule CGRP receptor antagonists in the …

Aims Chronic migraine (CM) is a common neurological disorder with complex pathogenesis.
Evidence suggests that pituitary adenylate cyclase-activating peptide (PACAP) induces …

Objective To review the role of CGRP in human models of primary headaches and to
discuss methodological aspects and future directions. Discussion Provocation experiments …

Calcitonin gene-related peptide (CGRP) is expressed throughout the central and peripheral
nervous systems, consistent with control of vasodilatation, nociception, motor function …

Migraine is the second leading cause for disability worldwide and the most common
neurological disorder. It is also three times more common in women; reasons for this sex …