Adipokines are cell-signaling proteins secreted by adipose tissue that has been related to a
low-grade state of inflammation and different pathologies. The present review aims to …

It is well established that adipose tissue, apart from its energy storage function, acts as an
endocrine organ that produces and secretes a number of bioactive substances, including …

The worldwide epidemic of obesity has brought considerable attention to research aimed at
understanding the biology of adipocytes (fat cells) and the events occurring in adipose …

Besides its role as an energy storage organ, adipose tissue can be viewed as a dynamic
and complex endocrine organ, which produces and secretes several adipokines, including …

Obesity is a well-known risk factor for the development of insulin resistance, type 2 diabetes,
dyslipidemia, hypertension, and cardiovascular disease. Rather than the total amount of fat …

Adipose tissue has traditionally been defined as connective tissue that stores excess
calories in the form of triacylglycerol. However, the physiologic functions attributed to …

In the mid-1990s, the interest in adipose tissue was revived by the discovery of leptin. Since
then numerous other hormones have been isolated from white adipose tissue that has no …

Diseases originating from altered energy homeostasis including obesity, and type 2
diabetes are rapidly increasing worldwide. Research in the last few decades on animal …

Obesity plays a causative role in the pathogenesis of the metabolic syndrome. Adipokines
may link obesity to its co-morbidities. Most adipokines with pro-inflammatory properties are …

The discovery of leptin in the 1990s led to a reconsideration of adipose tissue (AT) as not
only a fatty acid storage organ, but also a proper endocrine tissue. AT is indeed capable of …