Integration of the analytical framework and experimental tools of metabolic engineering with
emerging technologies such as DNA microarrays and directed evolution stands to …

Metabolic engineering aims to improve the production of economically valuable molecules
through the genetic manipulation of microbial metabolism. While the discipline is a little over …

Prokaryotes modified stably on the genome are of great importance for production of fine
and commodity chemicals. Traditional methods for genome engineering have long suffered …

While academic‐level studies on metabolic engineering of microorganisms for production of
chemicals and fuels are ever growing, a significantly lower number of such production …

Publisher Summary This chapter discusses several industrial fermentation examples. The
methodologies used in metabolic engineering and the challenges and approaches …

Metabolic engineering allows development of microbial strains efficiently producing
chemicals and materials, but it requires much time, effort, and cost to make the strains …

The field of metabolic engineering, loosely defined as the manipulation of living organisms
to achieve a desired metabolic objective, has grown and advanced significantly over the …

These microbes serve as natural sources of a large variety of compounds with the potential
to serve the ever growing, medicinal, chemical and transportation needs of the human …

Every year, we consume about 27 billion barrels of fossil oil. This enormous amount of oil is
used for fueling our cars and airplanes and also for making the various chemicals and …

Highlights•Systems-level insight into production strains enables predictable metabolic
engineering.•Multi-omic studies of production and platform strains are increasingly …