Tissue engineering needs a biomaterial as a framework for single cells to build a vital and
well functioning tissue. A future challenge is to modify biomaterials used this purpose in a …

The man-made creation of tissues, organs, or even larger organisms was for a long time a
matter of myth and dream throughout the history of medicine. It now comes into clinical …

Regenerative Engineering | Science Translational Medicine news careers commentary
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Stem cell-based therapeutics have gained tremendous attention in recent years due to their
wide range of applications in various degenerative diseases, injuries, and other health …

Although the biological functions of cell and tissue can be regulated by biochemical factors
(eg, growth factors, hormones), the biophysical effects of materials on the regulation of …

Cell therapy has already had an important impact on healthcare and provided new
treatments for previously intractable diseases. Notable examples include mesenchymal …

Cell transplantation holds immense potential for reversing diseases that are currently
incurable and for regenerating tissues. However, poor cell survival, cell aggregation and …

Stem cells are self-renewing cells that can be differentiated into other cell types.
Conventional in vitro models for studying stem cells differentiation are usually preformed in …

Tissue generation by autogenous cell transplantation is one of the most promising treatment
concepts being developed as it eliminates problems of donor site scarcity, immune rejection …

As stem cells are a cornerstone of regenerative medicine, research efforts have been
extensively focused on controlling their self-renewal and differentiation. It is well-known that …