Phase 1 dose escalation study of SBRT using 3 fractions for locally advanced pancreatic cancer

M Reyngold, SD Karam, C Hajj, AJ Wu… - International Journal of …, 2023 - Elsevier
Purpose The optimal dose and fractionation of stereotactic body radiation therapy (SBRT) for
locally advanced pancreatic cancer (LAPC) have not been defined. Single-fraction SBRT …

[HTML][HTML] Stereotactic body radiotherapy for the pancreas: a critical review for the medical oncologist

SK Kim, CC Wu, DP Horowitz - Journal of gastrointestinal oncology, 2016 - ncbi.nlm.nih.gov
With recent advances in imaging modalities and radiation therapy, stereotactic body
radiotherapy (SBRT) has allowed for the delivery of high doses of radiation with accuracy …

Dose escalation of Stereotactic Body Radiotherapy (SBRT) for locally advanced unresectable pancreatic cancer patients with CyberKnife: protocol of a phase I study

SW Qing, XP Ju, YS Cao, HJ Zhang - Radiation Oncology, 2017 - Springer
Background Dose escalation of SBRT for locally advanced pancreatic cancer patients had
been reported in several studies in one or three fractions, and phase I protocol was …

Application of stereotactic body radiotherapy in advanced pancreatic cancers in Australia

L Kim, N Nguyen, N Singhal, VA Phan… - Journal of Medical …, 2019 - Wiley Online Library
Introduction The majority of pancreatic cancers present locally advanced and carry a high
mortality rate. Treatment is challenging, with mixed data suggesting use of chemotherapy …

[HTML][HTML] Stereotactic body radiotherapy for pancreatic cancer–A systematic review of prospective data

MA Shouman, F Fuchs, F Walter, S Corradini… - Clinical and translational …, 2024 - Elsevier
Purpose This systematic review aims to comprehensively summarize the current prospective
evidence regarding Stereotactic Body Radiotherapy (SBRT) in various clinical contexts for …

SBRT in pancreatic cancer: what is the therapeutic window?

TB Brunner, U Nestle, AL Grosu, M Partridge - Radiotherapy and oncology, 2015 - Elsevier
Purpose/objective: To analyse outcome and toxicity of stereotactic body radiotherapy
(SBRT) in pancreatic cancer (PDAC). Material/methods: We systematically reviewed full …

Phase 2 multi‐institutional trial evaluating gemcitabine and stereotactic body radiotherapy for patients with locally advanced unresectable pancreatic adenocarcinoma

JM Herman, DT Chang, KA Goodman, AS Dholakia… - Cancer, 2015 - Wiley Online Library
BACKGROUND This phase 2 multi‐institutional study was designed to determine whether
gemcitabine (GEM) with fractionated stereotactic body radiotherapy (SBRT) results in …

Stereotactic body radiation therapy: a new standard option for pancreatic cancer?

JM Herman, AC Koong - Journal of the National Comprehensive Cancer …, 2014 - jnccn.org
For many patients, a pancreatic cancer diagnosis involves a dismal (< 6%) chance of
survival beyond 5 years, and little progress has been made in terms of prevention and early …

Re-Irradiation With Stereotactic Body Radiotherapy for In-Field Recurrence of Pancreatic Cancer After Prior Stereotactic Body Radiotherapy: Analysis of 24 …

Y Shen, X Zhu, F Cao, H Xie, X Ju, Y Cao… - Frontiers in …, 2021 - frontiersin.org
Purpose/Objectives Locally recurrent pancreatic cancer is a therapeutic challenge, and
aggressive approaches are needed to improve its clinical outcomes. Stereotactic body …

One-vs. three-fraction pancreatic stereotactic body radiation therapy for pancreatic carcinoma: Single institution retrospective review

PA Sutera, ME Bernard, BS Gill, KK Harper… - Frontiers in …, 2017 - frontiersin.org
Background/introduction Early reports of stereotactic body radiation therapy (SBRT) for
pancreatic ductal adenocarcinoma (PDAC) used single fraction, but eventually shifted to …