Polyglutamine diseases are autosomal dominant, late-onset neurodegenerative disorders.
Expansion of a polyglutamine (polyQ) tract above a threshold size leads to misfolding and …

Protein aggregation is a key mechanism involved in neurodegeneration associated with
Alzheimer's, Parkinson's and Huntington's diseases. Nine diseases (including Huntington's) …

The polyglutamine (polyQ) diseases are a group of inherited neurodegenerative diseases
caused by the abnormal expansion of a CAG trinucleotide repeat that are translated into an …

The presence and aggregation of misfolded proteins has deleterious effects in the nervous
system. Among the various diseases caused by misfolded proteins is the family of the …

The polyglutamine (polyQ) diseases, such as Huntington's disease and several types of
spinocerebellar ataxias, are a group of inherited neurodegenerative diseases that are …

Polyglutamine (PolyQ) diseases are a group of neurodegenerative disorders caused by the
expansion of cytosine–adenine–guanine (CAG) trinucleotide repeats in the coding region of …

The polyglutamine (polyQ) diseases, including Huntington's disease and spinocerebellar
ataxias, are classified as the protein misfolding neurodegenerative diseases like Alzheimer's …

Polyglutamine/poly (Q) diseases are a group nine hereditary neurodegenerative disorders
caused due to abnormally expanded stretches of CAG trinucleotide in functionally distinct …

Polyglutamine diseases comprise a class of familial neurodegenerative disorders caused by
expression of proteins containing expanded polyglutamine tracts. Great progress has been …

Mutant protein aggregation is a hallmark of many neuro-degenerative diseases, including
the polyglutamine disorders. Although the correlation between aggregation formation and …